Description
Effector protein that participates in the suppression of macrophage apoptosis by blocking the extrinsic pathway. Interferes with caspase-8 activation and binds to the host E3 ubiquitin-protein ligase RNF213, whose fusion partners have anti-apoptotic function.
Species
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Sequence
MEAALAIATLVLVLVLCLAGVTAVSMQVRCIDAAREAARLAARGDVRSATDVARSIAPRAALVQVHRDGEFVVATVTAHSNLLPTLDIAARAISVAEPGSTAARPPCLPSRWSRCCCASPVRVHI
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service