Does not exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the activity of ANO1 (By similarity).

Belongs to the anoctamin family.

646 amino acids

MQLGLSVSDSDASPFTPLAVLELAHDTKAEAIAWLLNRIRDKQRNGGAELLVDQLLFPAQDGQKPNPNVFVVGSTLQRLLSGAEDVGLFKEFQDGTMRGFTYANRESFKDFEGDGEGFLGDAECQYIVKHELDTLRAKNEEYIPGYPKYKLYPGKSIVRRLQSKGVLVQYFPLHNKEDLKRLSFSWYKKIKLSFQPLDDIRSYFGEGLGLYFGFLEYFTFALIPMALIGIPYYLFDWEDYDKYVLFAVFNLVWSTVFLEVWKRCSATLAYSWGTLGRKKAFEEPRAGFHGPLGLNPVTGREEPIYPSSKRHLRIYLVSVPFVLLCLYLSFYVMMVYFDMEFWAISIYHENPNFATSVLLFVPSIIYAVVIEIMNLLYRYAAEFLTDWENHRLESSFQNHLVPKVLVFNFVNCFASLFYIAFVMQDMVLLRQSLATLLITSQILNQVMEAFLPYWLQRRRNKRVYKRMRRLMGDKELPLLEQIQLETEMNTYLGTFDDYLEQFLLFGYVSLFSCVHPLAAVLVVLNNITEVYSDAFKMCHVFKRPFSEPAANIGVWQLAFETMSIIAVVTNCALIALSPQVKAYFPESDAQLILTVVAIEHVLLAFKFILAFVIPDVPKHIQVKLSKLDFESLEALKKRKILEVAET

74.5 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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