Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

Belongs to the cullin family.

907 amino acids

MFQNKEQTESILVWEKIVSIFSIPSQNEILNFKQKSPNNIDNNLKQLFNFVKLYKLESLVLDWYFESIKKYFKSTLSNEFWKFFNNVNLAELDSSTTSGRQLKFINHQFALSINLLHKVFSFFKSNLFLFYELLFKKESYNFNFLIKKLQDLLITNIMHTTNQQTKYFNTILFMFFERDFISFTKSFYHSKKQILKDEEENNNNSKDLEFNDQQQEEEEEEEENEEESKSYIIMEMSFEDSITDINIKEDSFMDLCKKLQDLNFIVISEEIFTQILFKKVFEYIETRCKGVFEKSFLKSILEWADQVIFKWLAMILLSSTTTTKINNYNDIINNNDDDNDDDDDDENKENSLKIFNQWKKRLEFSIYENYSQQRISELFDMIVQYPDSLPSLEDLSICFQKIPIEKTMITNLKRVLHNRLLHPGANTSDIITQYISTIHAMDIIDPSGMVMEKVGKPIREYLSQREDTIRCIISSFTEESNEIYQELCNYDPQDNGGDDDSNNSLLAFGNCDLYVDEGDNFSSIDDFKFWIPNKIDGSSTTISIGNAKANNNNKKKKKKDTISHLVNIYDGIDLFINEYRSMLSDRLLSVVDFDLDKEIKNIELLKLRFGDSVLFNCEIMIKDMVDSKRLNLQIKNSQGVNNNNNNNNNNNNELKEFETLILSQLFWPTLKGDEFKYPKSIEKKMQIYSKEYERIKTPRQLIWKQHLGLVDLDLEIGNNIQSFQVSPIHATLIMLFESDDGDDDDEKELTLEYLSKQLEISKDLVKKKLIFWLNNQIIKETSHETYKINNKEKEEQKQRQQQIENDDQDESSSDDDDDDNNIVVEEEEEEKSTSAKEKEEQMRVVESFIIGMLINFKTLPLERIHSMLTMFNSELYTSTIHELKAFLSKLVNEEKIELVGNDFKIKK

107.1 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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