Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism (By similarity).

Belongs to the aldehyde dehydrogenase family.

539 amino acids

MWRVPGLLCVRVARKSKFSGSWNRPAAFMSTLLINQPQYAWLKELGLREENDGVYNGSWGGRGEVITTYCPANNEPIARVRQASMADYEETVEKAREAWSIWADVPAPKRGEVVRQIGDALREKIQVLGSLVSLEMGKILVEGVGEVQEYVDVCDYAVGLSRMIGGPILPSERPGHALIEQWNPVGLVGIITAFNFPVAVYGWNNAIAMICGNACLWKGAPTTSLISVAVTKIIAKVLEDNKLPGAICSLTCGGADIGTAMAKDERVDLLSFTGSTQVGKQVALMVQERFGRSLLELGGNNAIIAFEDADLSLVVPSALFAAVGTAGQRCTTARRLFLHESIHDEVVNRLKKAYAQIRVGNPWDSNVLYGPLHTKQAVSMFLGAVEEAKKEGGTVVYGGKVMDRPGNYVEPTIVTGLDHDASIVHTETFAPILYVFKFKNEDEVFAWNNEVKQGLSSSIFTKDMGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSKDLPLAQGIKFQ

58.6 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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