Alpha-1,2-mannosyltransferase required for cell wall integrity. Responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides. Addition of alpha-1,2-mannose is required for stabilization of the alpha-1,6-mannose backbone and hence regulates mannan fibril length; and is important for both immune recognition and virulence.

Belongs to the MNN1/MNT family.

660 amino acids

MFQQLTYRLRLFRRRHKYIFINSIFLSVIIIFLIYSYWSNLPAEDNSAIINEKGTYHRSLWESITMALFPPKTKPFEEKKPQVNPNNNQEVGVESGASEISQHKQQQQQQQHAKEPTTKTSSKSLVSDEAYQLNLKLINEQQEKYNRLHPFEQKRLQQGYEFFDNIFKIFYQAKPSVSQLNTYPSKKRIYHARFDSLADDDTIFSEKYLSQFLQLSNEELAAMKKSHKYVVENLPEDAPDGLYKKNGIVYVAGGSFNWLTLLSIKSLRAVGCHLPIEVFIPKIEEYESDLCNRILPELDARCIYMKNQLMNPNKDNSDSFANKFEFKGYQYKALAILLSSFENVLLLDSDNIPAHSPEELFENDPFKSYGLVVWPDYWKRATSPYYYNIADIDVSEKYLGSKYNEVEGQYTDLSVEKGSVELDKIPLHQRLGSIPDPTSESGQLLISKKTHLKPLLLALYYNLYGPSHYYPLFSQGSDGEGDKETFLAATVTLGKRYYQVAKFLVSLGHFKVPGGDFEGCGMGQFDPQQDLEYIKLREQYAKIPEKDKEKQHKFKLQHQVLEKGPEILFVHANFPKLNPWKLKQEKKIFDAKGNRVRLYGPGMIKRIGYDFEWFQWEGMKYLLCIYDVNLQIFQDVKKSDLCDEILEHLRFLESTQNITD

76.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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