Protein expression services for AGRN | Agrin
Description
Plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Ligand of the MUSK signaling complex that induces the phosphorylation of MUSK, the kinase of the complex. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the transcription of specific genes and the clustering of AChR in the postsynaptic membrane (By similarity).
Species
Diplobatis ommata
Fragment
single
Length
1328 amino acids
Sequence
VPLSPVCGSDGVTYDSECALKLMRCMIQKDLHVVMLSPCKDASPSSVPELHCSRSVYGCCRDNVTAAQGVGLAGCPSTCECNRYGSYSKTCSPSSGQCSCKPGVGGLKCDRCEPGFWNFRGIVTDEKSGCTPCNCYPLGAVRDDCEQMSGLCSCKAGISGMKCNQCPNGSKLGPSGCDQDPSVSRTCSDLHCQYGATCVQSIGRAYCECPPSICPKNKQFKVCGSDGVTYANECQLKTIACRQGSVINILHQGPCQGTTPSTGNIQTTDLTPSPKEHTNLSKIVSLETIPILKAIFPVTDNTTGPQVHKMYTVTASPGVIGHPTAGWPPSSLTSSEPPDLSGSGDFSGDTDLEASGNLEGSGVEPMGFNESSTGPPTPVPNERSTCDNTEFGCCSDGKTPSVDGEGSNCPPTKLFQGVLIVEEVEGQELFYTPEMDDPKSELFGETARSIENALNELFGNSNVKKDFKSVRVHGLGPSDPVRIIVEVHFDPRTSYNSHDVQRALLQQVKQSRRKSIVVKKPEQDNVKIVDFDWAPLLFTTTSTTAARTTVPITTASALPVTRRPPPATTRWPKVLPHAKVPSTTTKPATTRRPPFSRKVEVRPATVKVHRPCDSQPCLHGGTCEDDGVSYTCSCPAGRGGAVCERTIVYFIPEFGGRSYLAFKTMKAYYTVRISMEFRASNLDGLPLVQWTEKGKGLHFYRPSEGYVELRFNHGVWDGVITSKTLIKPGNWHHVVGNRNRRSGMLSVDGEPHLIGESPPGTDGLNLDTDLFLGGTPEDEMTLVTERTTATKGLQGCIRLLDVNNLIYDLQERSNDVLYGSGVGECGNNPCSPNPCKNRGKCHMKEAEMFHCESVGEFSGPTCADKHNPCDPNPCHQSANCMVLPEGGSKCECPMGREGELCERVSEAEQDQGKAFIPEFNGLSYLEMNGIHTFVSDLLQKLSMEVIFLAKDPNGMIFYNGQKTDGRGDFVSLNLRDGYLEFKYDLGKGAAVLRSKAPIPLNVWNVVTVERNGRKGLMKINKDELVSGESPKSRKAPHTALNLKEAFYVGGAPDFNKFARAAGIISGFTGAIQKLSLKSIPLLKKENIRNAMEISNFRWHACTKTRNPCQNGGVCSPRLREYDCMCQRGFSGPQCEKALEEKSASGSESVAFNGRTFIEYHNTVTRSEKAVQVNYFEMSIKTEATKGLILWSGKIAEKSDYIALAVVDGFVQMTYDLGSKPVTLRSTIPVNTNQWVRIKANRIHGYGTLQVGNEAPVTGSSPFAATQLDTDGALWLGGIEKLAPGNRLPKAYSTGFIGCIKDVVIDRQELQLVEDALNNPTILHCPAKK
Mass
144 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service
Make AGRN using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)
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