Major cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Acts as a downstream effector of the EFG1 regulatory pathway. Required for rapamycin-induced aggregation of C.albicans. Binds glycans and mediates adherence to endothelial and epithelial cells, thereby playing an important role in the pathogenesis of C.albicans infections.

Belongs to the ALS family.

1260 amino acids

MLQQFTLLFLYLSIASAKTITGVFDSFNSLTWSNAANYAFKGPGYPTWNAVLGWSLDGTSANPGDTFTLNMPCVFKYTTSQTSVDLTADGVKYATCQFYSGEEFTTFSTLTCTVNDALKSSIKAFGTVTLPIAFNVGGTGSSTDLEDSKCFTAGTNTVTFNDGDKDISIDVEFEKSTVDPSGYLYASRVMPSLNKVTTLFVAPQCENGYTSGTMGFSSSNGDVAIDCSNIHIGITKGLNDWNYPVSSESFSYTKTCTSNGIQIKYQNVPAGYRPFIDAYISATDVNQYTLAYTNDYTCAGSRSQSKPFTLRWTGYKNSDAGSNGIVIVATTRTVTDSTTAVTTLPFNPSVDKTKTIEILQPIPTTTITTSYVGVTTSYSTKTAPIGETATVIVDVPYHTTTTVTSEWTGTITTTTTRTNPTDSIDTVVVQVPSPNPTVSTTEYWSQSYATTTTVTAPPGGTDTVIIREPPNHTVTTTEYWSQSFATTTTVTAPPGETDTVIIREPPNHTVTTTEYWSQSYATTTTVTAPPGGTDTVLIREPPNHTVTTTEYWSQSYATTTTVTAPPGGTDTVIIREPPNYTVTTTEYWSQSYATTTTITAPPGETDTVIIREPPNHTVTTTEYWSQSYATTTTVTAPPGGTDTVLIREPPNHTVTTTEYWSQSYATTTTVTAPPGGTDTVLIREPPNHTVTTTEYWSQSYATTTTVTAPPGGTDTVIIREPPNHTVTTTEYWSQSYATTTTVTAPPGGTDTVIIREPPNYTVTTTEYWSQSFATTTTVTAPPGGTDTVIIYESMSSSKISTSSNDITSIIPSFSRPHYVNSTTSDLSTFESSSMNTPTSISSDGMLLSSTTLVTESETTTESICSDGKECSRLSSSSGIVTNPDSNESSIVTSTVPTASTMSDSLSSTDGISATSSDNVSKSGVSVTTETSVTTIQTTPNPLSSSVTSLTQLSSIPSVSESESKVTFTSNGDNQSGTHDSQSTSTEIEIVTTSSTKVLPPVVSSNTDLTSEPTNTREQPTTLSTTSNSITEDITTSQPTGDNGDNTSSTNPVPTVATSTLASASEEDNKSGSHESASTSLKPSMGENSGLTTSTEIEATTTSPTEAPSPAVSSGTDVTTEPTDTREQPTTLSTTSKTNSESVATTQATNENGGKSPSTDLTSSLTTGTSASTSANSELVTSGSVTGGAVASASNDQSHSTSVTNSNSIVSNTPQTTLSQQVTSSSPSTNTFIASTYDGSGSIIQHSTWLYGLITLLSLFI

132.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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