Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.

Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.

921 amino acids

MGKKQEKKTAKGRLDKFYWLAKEQGYRSRAAFKLVQLNKKFNFLEKARCCIDLCAAPGGWLQVASKFMPANSLIVGVDLVPIKPIPRTITFAEDINSYKCRDQLRQILKDWKADIVIHDGAPNVGTAWVQDAYAQSELTLQSLRLAVEFLTAGGTFVTKVFRSKDYNNLLWVFNQLFKKVEATKPSSSRNVSAEIFVVCQGYKNPARIDPKFLDPRHVFKELDPASLADQDQEAGVPLSLKGTSAGNAHANVFEPKKIRRNREGYADGDYTLFHSLDAMDFIKGQDVIGMLGSYNQISFESDESKKLLSLPDTNDEMRENCSDLKVLGKKDFRNLMNWRKEVRLALGIDLPKSKHQDLAEQTQTVEVEEMDEDDQIDDELARLNEEAARKARKERRRKNELRQKKILKMQLQMTTPMDIGMDVMDDQLGAGNGDMFEISSGERVSKKALIQQADVSDDESETIVSSQHTDDDDPETRARRLDAEMDALYDEFKQKQSERDAKFRAKQARLQDAKNDSWHGIKDDEENDEDDDEANLSDESEGGYDLVQRRKEQEETFDTDDEEDEEDERLEREATQHSKKRKRDLAAPTADSFEMDAKPPKRSLVHSLVSDADVSAQQSREASIWFDNPLFKDLELDEQDAQEALEDDQDDEDAWEEEQDDEDDAEESDSEVEGEQEVEDDDFEVVPQDQEEHAIPDEEWDLNGEDEEAGKQKRIKDHGLATAEAVALAQALVNRQITKEDLMDQGFSKHNFVDKDGLPTWFLDDEQKHYKANIPITKEAIQALRERQRALDARPIKKVAEAKARKKMRTLRRLEKAQKKAETINENEDISEKEKSNTINKLLAKSVKGAQKKKEVQLVVAKGVNRGLKGRPKGTKGRYKMVDPRMKKELRAFKRKAKRDGKKLGSSNSKPRVPKGYGPRN

105.1 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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