Plays an important role in the salvage pathway for purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).

Belongs to the adenylosuccinate synthetase family.

710 amino acids

MPVRRYGGRYNNSSPGVSNALSPSTTAGRPLSPSPAAGSKLASTHHDPVPQEAYYVNDEADARHQQQAPFREPSVEVEVEMIDDEPPHGSQKPLSVAPYTANASNSSGRSKRNAITASGYTFYTNERQKTVYEALRSLRPLAELQEPRRVKEYAETSLKDSLYRIIEAHDVIMVAGAFFGDEGKGKTVDAVAHHPLCTCIARVNSGENAGHTVYDKAGRKFVFNLAPSGLLLPGKRNYIGPECVMDPVSFMEKEVIQLIDAGIDYRDRLFIGNVCIVTPYHKLLDLLGSAANSSTLKGMAPVHGSKVMKRGIRLDHIFNDDETLRKRLEKDMDTYLGLLKVKNLSDADVVRLCREENSDGVVRVPDYVIAFAQAKVKVEFLVKLYRDRVRHNPDFPARCDVTYELHAAVLRGEKVLLEGPQSYWLSNARTKFWESTTSADTTAAGLLAASQLNFQKFKSVVLNVHKAPGSSRVGIGACPSSFVPQDYFSAQNIKTLRDLPSETCANFEAVQRTLFRDGFPHSNDKARHNGIMAPVEYSDETGKYNIGVAMAIASAQHHGECGAVTKKPRVCGFFDCVLQHEVNSIQGPYLTISALDRGDEYDKVGVTIAYVYYNPEGKQVDVNGHVYKNGDIIRAGDPVPSEPALYHCHPIVKLIDGWRDNPIAAAKRRRNAPLPRGVCELLSTIEYFTNCKILSIGNGPNGDDIIYLRQ

78.4 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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