Implicated in both actin filament depolymerization and polymerization. May enhance chemotaxis by promoting cofilin-dependent actin assembly at cell leading edges.

Belongs to the WD repeat AIP1 family.

597 amino acids

MSVTLKNIIAPTPATTRGKSVAINGDPKGENIVYASGSSIIIRNVKNPMVADIYYEHPCQTTVAKYAPSGNYIASGDVQGNLRIWDTLQKEHILKATYKVLNGAILDIAWTSDNQRLVVVGDGKERFGAAILWDSGSSCGEITGHSKMILSCDIKSTRPFRAATGSEDFAVNWFEGPPFKFQKNIAAGDFTRFVNCVRFSPDGNKLVTVGADKKAFVYDGKTGEKLIELNPAQQHTGGIYGCSWSADNNRVLTASADKSCKIWDTTTGQCINSFTFGSDVNDQQLGCLWFGDSLLSVNLAGEISTLNLDDVAKPSRVIKGHNKLVGTIAFDKNAGSLYSASYDASLLQWDLSTGLATNFTGPAHKNQITSIKINGDQLITCAMDDSVKISSISKKTYGESIGVDSPAQAVAFSGDVVVAVSMKTIYVIKGGKIVSQTAATWEPTSVAINDTEVSVGGKDNKIHVFTLSGNNLTASHTLDNHRGAITDLSYSPCGKYLASGCSNREVIVWSGKEAKSKGWVNHTARINAVAWSNDSKFVASASLDSQIYIWNVENPTASPVQVKNSHLGGVNDVIYGSNNEIFSAGNEGAIKIWNVSN

64 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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