ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5.8S rRNAs.

Belongs to the DEAD box helicase family. DDX51/DBP6 subfamily.

593 amino acids

MKDADDSEEVKEEQAKGTKKGRKSSEPAATENDDDKPTKNKFAGILSKFERSKKARELEKTRESTKDEDSTEPTTAEPVIAQGLEPLPQPEAAPEQDEMPTYSSLPPWLANPLRASAQERRKFADLGIDSSLLRVLEDNGYREAFAVQSTVIPLLLQGPTNHPGDLCISAATGSGKTLSYVLPLVTALKPLPAPRLRGLIVVPTRELVKQAREACELCAAGSGLRVASAVGNVAIKDEQRESLPGYVHRSEPNVDILICTPGRLVDHLRYTKGFTLKNLEWLVIDEADRLLNESFQEWVDVVMTSLDARKAPDAFGFSGNFLSGLGLPIQSKEPRKVVLSATMTRDVTKLNSLRLANPKLVVIGSDAAATEDESGGVAPSDEQFTLPPTLEEHTVSVGDGSQKPLYLLRLLLSHIKLETKILVFTKSSESASRLARLLALLEPSLSDRIGTIIKSNKSSASRKTLTAYRRGKISVIIATDRASRGLDLRSLTHVVNYDVPASITTYVHRVGRTARAGQKGSAWTLVAHREGKWFASQIAKGSDGKITRSTKVGKVQFKLDNMKEVKARYASALDLLEKEVKTGGTKASKPSAQ

64.6 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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