ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity).

Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.

450 amino acids

MADGIDRTAEERMEFTTSKEVTVAPTFEDMHLKENLLRGIYAYGYESPSAVQSRAIVQICKGRDTIAQAQSGTGKTATFSISILQVIDTVLRETQALVLSPTRELATQIQSVVMALGDYMNVQCHACIGGTNVGEDIRKLDHGQHVVSGTPGRVADMIRRRHLRTRHIKMLVLDEADELLNRGFREQIYDVYRYLPPATQVVVVSATLPYDVLDMTTKFMTDPVRILVKRDELTLEGLKQYFIAVEKEEWKFDTLCDLYDTLTITQAVIFCNTRRKVDWLTDKMREANFTVSSMHGEMPQKERDSIMQDFRQGNSRVLISTDVWARGIDVQQVSLVINYDLPSNRENYIHRIGRSGRFGRKGVAINFVTSEDVRILRDIELYYSTQIDEMPMNGTLFYLRYRPMSRLSLWLTQSNSCRPSHVTTLSWSTNVEHTFPLLLMNAFSKIQIGI

51.5 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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