DNA-dependent ATPase and 5'-3' DNA helicase that efficiently unwinds G-quadruplex (G4) DNA structures. May be involved in resolving commom issues that arise during DNA replication, recombination, and repair.

Belongs to the helicase family. PIF1 subfamily.

439 amino acids

MNSESKCYRFYICFARLGSGMIAGLMPVHEIELSPEQASALDLLRSGENVFLTGGAGSGKSFLIRQFMRELDPKEMPILASTGAAAVLLGGRTFHSFFGLGIMEGGADATYERASKDKRLMSRLRKVEGVIIDEISMIPGQALMIAEALSQRARESKLPWGGMRVIAVGDFAQLPPVTHTGQRDWCFLNGVWEVSGFQTVMLSHNQRVSDNLFLDVLSDVRHGKVTERVREFLNEHVQDHDEDDPGTRLFPRKINAEKFNERKLAEIDETEVVIESIYSGSERHIETLKKASPIAEKLILKIGCQVMFLQNDPQRRWVNGTRGTVVDITADQITVRKDRGREVQVSKSSFAIQDAEGNIMAQVEQFPLTLAYATTIHKSQGATLDDLWCDLSQLWEPGQAYVALSRLRSAKGLHLIGWNPRSIIVDPKVLHFYKQFEGL

49.1 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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