Protein expression services for KU80 | ATP-dependent DNA helicase 2 subunit KU80
Description
Single-stranded DNA-dependent ATP-dependent helicase. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair. When associated with KU70, binds to double-stranded telomeric and non-telomeric DNA sequences, but not to single-stranded DNA. Plays a role in maintaining telomere length. Acts as a negative regulator of telomerase (By similarity).
Family
Belongs to the ku80 family.
Species
Oryza sativa subsp. japonica
Length
688 amino acids
Sequence
MARNKEALVLLLDVGPSMHGVLQEVENICSTLVHKKLVYNRSDEIGVVLFGTKETSNELAKELGGYKHVVVARDIKVVDEETTNALQNLPRGTSPGDFLDAIVVGLDMLIRKFGNIKGKQRMCLVTDAQHPLRDPPQGTKKDQVDTIADQMKRHEIKMDCIIFRESGVRHNAVMDENDQLLYHFRERSVTKVVHVDSPTSLLGALRTRNVLPVTVFRGDLEVSSSFKIKVWVYKKTSEEKFPTLKKYSDKAPASDKFASHEVKVDYEYKSVLEPDTVVPPDQRIKGYLYGPQVVPISSAEWEAVKFKPEKGVKLLGFTDRSSISRHYFMKDVFSFVPEPGNTKAVAAVSALARAMSEMNKVAILRCVWRQGQGNVALGVLTPNISSAKNVLDSFYFNILPFAEDIREFQFRSFSSLPSSSQPTKEQQEAADNLVKMLDLAPPGREEILKPDFTPNPMLERFYRYLDLKSKQPDANVPPLDKCLKKITEPDPDVIDYQAPLIKKLGNVFELKENPKKKKARTQDRLTYTGADDQAKLLEEPSAEKVGVSEALYPPKKKAGEIGDHNPVQDFEAMLTQRSSSTWVQTAIEEMQKYITALIQDSCDRDNHQKALECLVALRKACIIEQEPNEYNGFVTKLCQKFRPAGDKIFLQLLSSKKASLISKEEAPDSDVTEEMARNFCLKPEPSSQ
Mass
77.4 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service
Make KU80 using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)
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