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Protein expression services for KU70 | ATP-dependent DNA helicase 2 subunit KU70

Description
Single-stranded DNA-dependent ATP-dependent helicase. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair. When associated with KU70, binds to double-stranded telomeric and non-telomeric DNA sequences, but not to single-stranded DNA (By similarity). Required for the maintenance of chromosome stability and normal developmental growth. Plays a role in maintaining telomere length. Acts as a negative regulator in telomere homeostasis.
Family
Belongs to the ku70 family.
Species
Oryza sativa subsp. japonica
Length
624 amino acids
Sequence
MDLDPEGLFRDDSDEDDDNVQEREANKEMVVYLIDASPKMFTPATKADEKEETHFHTIVNCITHALKTQIIGRSYDEVAICFFNTKEKKNLQELAGVYVYNVTEREPLDRPDARLIKEFSCIEDSFMSNIGSRYGITSGSRENTLYNALWVAQALLRKGSVKTVSKRIVIFTNEDDPFGGLTGAVKTDMIRTTIQRARDAQDLGLSIELLPLSRPDEEFNMSLFYADLIGLEGDEIVDYLPSSGEKLEDMTNQLKKRMMKKRKVKTLAFAITNDVCIEVNTYALIRSTTPGAITWLDSISNLPLKAERSFICNDTGALIQDPQKRFQVYNDKIVKFSTRELSDVKRVSSHHLRLLGFKPLDYLKDYHNLRPSTFIYPSDEQIFGSTRVFVALHSSMRRLGRFALAFYGNPTRPQLVALIAQEEVTSAGGQIEPPGIHMIYLPYSDDVRYPEEVHLTSDDAPRATDEQIKKASNLLRRIDLKNFSVCQFSNPALQRHYGILEALALGEDEMPDVKDETLPDEEGLARPVVVKAVEEFKASVYGENYDQEEAEAAAAKAGASKKRKALTDAAAEKSAAHNWAELADTGKLKDMTVVDLKSYLSAHGLPVSGKKEALVSRILTHLGK
Mass
70.1 kDa
Simulated SDS-PAGE
Western blot of KU70 recombinant protein(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service
Make KU70 using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)

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