General regulatory factor (GRF) that contributes to transcriptional activation of a large number of genes, as well as to DNA replication, silencing and telomere structure. Involved in the transcription activation of a subset of ribosomal protein genes. Binds the ARS-elements found in many promoters. Binds to the sequence 5'-TCN(7)ACG-3'.

Belongs to the ABF1 family.

494 amino acids

MSLYEYKHPIINKDLAAPDPVSAQKRSFPTLEAWYDVINDYEFQSRCPIILKNSHKNKHFTFACHLKSCPFKILLSYQGANNSGSSEDGSPHGLSGDGGSSSSGSNHHNGHTNLAEDGRAEDEDDDEDDDAAVTAAIAAAVAAVADSQETIKGPFVVTKIEPYHNHPLESNLSLQRFVLSKIPKILQVDLKFDAILESLCNDDDNTVAKFRVAQYVEESGILDIIKQRYGLTEAEMDKKMLSNIARRVTTYKARFVLKRKKDGVYAMPTAHQLTGGDHHQVQHHHHPSIPAHHQHQLPEGQQRDVQHHHQQQQQQLQHQEQHQSHVDSGHNVYQNRIGSISDNDDSAIHNLDDTNVRVAAAAAAAAAALQSRENHDTEDLKRTLEQVQDDESLDVGVPDSKRQLHRRERDRVAEALKMATRDILSNQSVDSDVNVDVDLVTGHKQLSPHDDMAEQLRLLSSHLKEVEAEENVSDNNLKKDDIPDENIQPELRGQ

55.3 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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