Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. The AP-1 complex interacts directly with clathrin (By similarity).

Belongs to the adaptor complexes large subunit family.

865 amino acids

MQTTHPKNLHLTCSGVERGFTNSPKTHPKMSSLKSFIKAVRASKTTAEEHTTILKESAQIRKNIRQGSNDMRMRRKNVAKLLYLFLLGEPTHFGQIECLKLLSSSRFMDKRLGYLAAMLLLDENQEVLTLLTNSLQNDLKSRDKFIVGLALSAFGNVAGPELARDLSNDIAELCSNHHNYISKKAVLCALRVIQKEPDLESLYIEKTDELLHSKSHGVLMAALAFAISACKINPSLISRFESQADDLIYRIRQLSTSTYSSEHNIGNISDPFLQVKILQFLSILGQNNPKIYDKMSDLLAQVCTNTDSSRNAGNAILYQAVRTILDLNSDSSLRVLGVNILAKFLGNRDNNTRYVALNMLKLVVNSEENAVQRHRSTILACLNDVDSSIQSRALELSTFLVNEANVRFMVRELLSFLDNVSDELRGSTAQYITEVTNAFAPNKRWHFDTLLRVFKSAGNFVSESTLSTFLRLIASAPELHEYAVVKLYAALKEDVSQEALTLSAFWVIGEYGQMLLSPTMNFDDDQTLPHSVSESDIVDIIEEVFNSVEASRYIIVQYGLFALTKLSARLGSSSTASRIDKIIYSYKRNKNTEVQQRSVEFHLILNDSKLSKTILEPTPAPLPPPRTTPYQNAEQKLKANKHVEKRVQESNELLDLIGLTTPSVAEPLETPVDEMTQSPQSSLSRAPSTSKKSHFEDILGLFASPAPSAQPVDSLASSFASLDFNASASQPSNNLSLLSSIPSTSKSYPPIVVFDKHDVTLTLVPSKEESTKTAVIEAKFKNKNPMTRVEKIHLEVAVPKSQKLKIQPLRTTSMEPGGETSQTLRVHGPSGSQVKLRLRISVVRQGGSNTLDQVDFGKLPSDLLQ

96 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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