Performs an essential function in the generation of cytoplasmic iron-sulfur proteins by mediating export of Fe/S cluster precursors synthesized by NFS1 and other mitochondrial proteins (By similarity). Not involved in the export of cyclic pyranopterin monophosphate (cPMP) from mitochondria to the cytosol.

Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.

680 amino acids

MMRVSQLQLCRTSLSYRLRSGYHHHHHLHHSFFKLIKRNSILESPPTNASHQSPSPITPMVNARVMFFSTSTSAPHPEKINRTSSENILRMISSYLWMKDNPKLCFRVISAFACLVGAKFLNVQVPFLFKVAIDWLSSSSFVDSNPYLVAAFATPSSVLIGYGIARSGSSAFNELRTSVFSKVALRTIRTISRKVLSRLHDLDLRYHLNRDTGALNRIIDRGSRAINTILSAMVFNIMPTILEISMVSCILAYKFGAVYALITCLSVGSYIAFTLAMTQWRIKIRKAMNEAENDASTRAIDSLINYETVKYFNNEDYEARKYDQLHENYEDAALQSRKSFALLNFGQSFIFSTALSTAMVLCSQGIMNGQMTVGDLVMVNGLLFQLSLPLYFLGVVYSDTVQGLVDMKSMFKFLEERSDIGDKDIDRKLPPLVLKGGSISFENVHFSYLPERKILDGISFEVPAGKSVAIVGSSGSGKSTILRMIFRFFDVDSGNVKIDGQDIKEVRLESLRSSIGVVPQDTVLFNDTIFHNIHYGNLSATEEEVYNAARRAAIHDTIMKFPDKYSTAVGERGLMLSGGEKQRVALARAFLKSPAILLCDEATSALDSKTEAEIMKTLRSLASNRTCIFIAHRLTTAMQCDEILVMEKGKVVEKGTHEVLLGKSGRYAKLWTQQNSKLEV

76.1 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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