Pleiotropic ABC efflux transporter that may be involved in A.fumigatus adaptation to azoles such as vorizonazole.

Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.

1274 amino acids

MALQQVRPTNKQCRKNKKRAKAKMMESPRRLCRWAIISYEGSPRIACNATDETAESPFLRNRERSSCINRGFDISYCVRCAFTPDEHCVWEPCCAIQSVRQQVEVGTSKRTMDIYSPLQFCFRVTGLRVSAVIRLEYVQALFSQPISKVDQVSVGTVTNTITTLSNTIQQSISDKLAILFQSLALLLAAFIIAFKYSWALTLVTSSALLFVVVGCSVTLPFMTKIQQKIDKADEKHSSIAAEVFGSIRTVISLGAQESLSKRYTTWVEEARKRGNGLSLIFGIHFALVFFALYASFSLAFWFGLKLYREGHIGEINTVITVFFSVMIVVSVLGNIASPLIIVSKAASAAGSFFELIDSEKVDSGGLREPDASAHVDIIFRDVRFTYPTRPDVPVLKGLDIRFQNGKTTALVGPSGSGKSTIVALIERWYQLAMSPEDQNQGSIYVGPHDINSLDLKWWRSQIGLVQQEPFLFNDTIFNNVAFGLIGTQWEKEPDSVKKELIEKACREAFAEEFIQRLPEGYATIVGQNGIKLSGGQRQRLAIARSIVKEPKILILDEATSAIDVRGEKIVQAALDRVSRNRTTIMIAHRLSTIRRADHIVVMKGGVNVEEGTHEELLQREGGVYRDLVNAQRLELLAEEDSHTGNAVLELQDEAQSPTMSVQEKLQDEDNTQDKNRGFIRTIGLVLYEQRARWPLYVAVLISTAGAGTAFPLQSWLFAKLIEVFRFTGQKLVDAANFWALMFFLLALAVGVLYSTVGFTANSLSVRISEACRKEYFQNILAKPIPFHDLSENASGSIVSRLATDPKQVQELIGLNGAFPLISTFSMIGCIAIAFSFGWKLSLVTVFAALPCTFLAAFMRIRYELQFEAMNAAVYAGSSQFAAEAIDAFRTVSSLTMEDAILDRYTQLLREQQKKAFRKARYATLIFAFSDSVELCAMALTFWYGGQLLASREYQPTSFFVIFMAIIQGGQSAGQFFSFASNFAQAAASANRILNSRPQSDELGAASIEKQQLVRSGDLTGATVEFHDVSFRYASQDVPLFTGLNVSIQSGQFVAFVGPSGCGKTTVISLLERFYSPSQGTITFNGEDIRTLEMTSYRRELSLVAQEPRLFEGSIRENITLGLDQSEFTEEELIQACKDAEIHDFITSLPEGYATELGIKAQTSLSGGQRQRLCIARALLRKPSLLLLDEATSSLDSQSEKVVQGAMERLAQKRSLTIVAVAHRLATIQKADTIYVFGTAHAGQASRIVEQGTHQELLRAKGTYWQMVSSPRFLT

141.3 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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