Protein expression services for ADAMTS4 | A disintegrin and metalloproteinase with thrombospondin motifs 4
Description
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Cleaves aggrecan at the '392-Glu-|-Ala-393' site.
Species
Bos taurus
Length
839 amino acids
Sequence
MSHMDSHPGRGLADGWLWGIQPRLLLPTVPVSGSRLVWLLLLASLLPSAWPASPLPREEEIVFPEKLNGSVLPGLGAPARLLYRLPAFGETLLLELEKDPGVQVEGLTVQYLGRAPELLGGAEPGTYLTGTINGDPESVASLHWDGGALLGVLQYRGTELHIQPLEGGAPNSAGGPGAHILRRKSPVSGQGPMCNVKAPPGKPSPSPRRAKRFASLSRFVETLVVADDKMAAFHGAGLKRYLLTVMAAAAKAFKHPSIRNPVSLVVTRLVVLGPGEEGPQVGPSAAQTLRSFCAWQRGLNTPDDADPGHFDTAILFTRQDLCGVSTCDTLGMADVGTVCDPARSCAIVEDDGLQSAFTAAHELGHVFSMLHDNSKQCTGLNGPESTSRHVMAPVMAHVDPEEPWSPCSARFITDFLDNGFGHCLLDKPEAPLHLPVTFPGKDYDADRQCQLTFGPDSRHCPQLPPPCAALWCSGHLNGHAMCQTKHSPWADGTPCGPAQACMGGRCLHVDQLQAFNVPQAGGWGPWGSWGDCSRSCGGGVQFSSRDCTRPVPRNGGKYCEGRRTRFRSCNTQDCPTGSALTFREEQCAAYNHRTDLFKNFPGPMDWVPRYTGVAPRDQCKLTCQTRALGYYYVLDPRVADGTPCSPDSSSVCVQGRCIHAGCDRVIGSKKKFDKCMVCGGDGSSCSKQSGSFKKFRYGYNNVVTIPAGATHILVRQQGSPSVRSLYLALKLPDGSYALNGEYTLIPSPTDVVLPGAVSLRYSGATAASETLSGHGPLAEPLTLQVLVAGNPQNARLRYSFFVPRPRPVPSTPRPTPQDWLRRKSQILEILRRRSWAGRK
Mass
90.3 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service
Make ADAMTS4 using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)
Order Here