Description
Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate. The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids. Also has weak activity for CMP. UMP and purine nucleotides are poor substrates (By similarity).
Family
Belongs to the pyrimidine 5'-nucleotidase family.
Sequence
MRLPVLGKDTVRMRDPEGLQDKITRIQRGGQEKLQIISDFDMTLSRFSRNGERCPTCYNIIDNSNIISDEGRKKLKCLFDIYYPLEIDPKKSIEEKYPLMVEWWSKAHDLFYEQRIQKDRLAQVVKESQATLRDGYDLFFNSLYQREIPLFIFSAGIGDVLEEIIRQAGVFHPNTKVVSNYMDFDDNGILTGFKGDLIHTYNKNSSVLKDTEYFKEISHRTNILLLGDTLGDLTMADGVSTVENIIKIGFLNDKVEELTEQFLQSYDIVLLRDETLDVVNGILQFVTAKN
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service