Description
Possesses 5'->3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote termination of transcription by RNA polymerase II (By similarity).
Family
Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
Species
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Sequence
MGIPAAFRWLSTKYPKIISPVIEDQPITMPDGTVIPVDATKPNPNGEEFDNLYLDMNGIVHPCSHPEDRPAPKDEEEMMVEVFKYTDRVVNMVRPRKLLMIAVDGVAPRAKMNQQRSRRFRAAREAMEKEEDKQKFVELLKKQNGKPQEEEPVEVVVKKAFDSNSITPGTPFMDILAASLRYWCSYKLNTDPAWANIKVIISDATVPGEGEHKIMEFVRSQRGSPNHDPNTRHVIYGLDADLIMLGLATHEPHFRVLREDVFAQDSRPRLCKICGQKGHDAMNCKGEAKEKNGEFDEKDAVVPLKPFIWLHVSILREYLAIELDVPGLPFQFNLERAIDDWVFMCFFVGNDFLPHLPALEIRENGIDTLTAIWKDNLPVMGGYLTKDGHADLERVQYIMAGLAKQEDAIFRRRKETEDRREAGFKRRKLADEARQRRAQGSRQIRQAAENSGPPAGFSFHKINEFPGKAPQPSITHDMVVNRQAVDQANVANKSAASVLKDQIKSMMAQGTSTPENGAESTETPAETAAAAPATEEQAAPPAALGKRKAELIEDAVAGPEASSTEVTEISESDAEPTDSVRLWEEGYADRYYEQKFKVDRKDIDFRHKVGRAYAEGLAWVLEYYFQGCPSWEWFYPYHYAPFAADFVDLGKMEIKFEKGRISRPFEQLMSVLPAASRHAIPEVFHSLMLEETSEIRHFYPDDFEIDLNGKKMAWQGVALLPFIDMPRLLAAMETKSHLLSPEDHLRNAPGKDYLLLSDSHPTLYDHITSQFYSKKQGTTKFELDPTKSAGLSGLVEKIDGYVPHGSLVYPLSRNSMPDVDYDRSLMVHYFFPDCSHTHKSMLLRGVQMPTPALTRSDIDILKGKASRSGRSYGGVPLSNKNYSGRNEPINYGPGGGQQGGRGRGGYQGGGGRGGGRGGYGGNGGGYQANGGGYYNGGNNGGGGGGYGGQPRDSYGPPPGWQPPPPPGLAGFGVGPPPPPPGAAYGGAPGGAGYGGYGSSRGGYQDNRYALPPPPPQAYQAQGQQYGQGGSRGGYQGQGNQYRGPPRQDRGYDNRGGYRGGGYRGGGDNRGYR
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service