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Protein expression services for sfmD | 3-methyl-L-tyrosine peroxygenase

Description
Heme-containing peroxygenase that mediates the hydroxylation of 3-methyl-L-tyrosine (3-Me-Tyr) into 3-hydroxy-5-methyl-L-tyrosine (3-OH-5-Me-Tyr) in biosynthesis of saframycin A, a potent antitumor antibiotic that belongs to the tetrahydroisoquinoline family. Involved in biosynthesis of 3-hydroxy-5-methyl-O-methyltyrosine (3-OH-5-Me-OMe-Tyr), a core structure of saframycin A.
Species
Streptomyces lavendulae
Length
365 amino acids
Sequence
MTAPADTVHPAGQPDYVAQVATVPFRLGRPEELPGTLDELRAAVSARAGEAVRGLNRPGARTDLAALLAATERTRAALAPVGAGPVGDDPSESEANRDNDLAFGIVRTRGPVAELLVDAALAALAGILEVAVDRGSDLEDAAWQRFIGGFDALLGWLADPHSAPRPATVPGAGPAGPPVHQDALRRWVRGHHVFMVLAQGCALATACLRDSAARGDLPGAEASAAAAEALMRGCQGALLYAGDANREQYNEQIRPTLMPPVAPPKMSGLHWRDHEVLIKELAGSRDAWEWLSAQGSERPATFRAALAETYDSHIGVCGHFVGDQSPSLLAAQGSTRSAVGVIGQFRKIRLSALPEQPATQQGEPS
Mass
38.2 kDa
Simulated SDS-PAGE
Western blot of sfmD recombinant protein(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service
Make sfmD using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)

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