Catalyzes the activation and addition of a nucleophilic thiol to the electrophilic epoxide substrate, which results in epoxide ring opening and the formation of an alcohol-nucleophile adduct.

Belongs to the vitamin-B12 independent methionine synthase family.

376 amino acids

MLIRGEDVTIPTSMVGNYPNPRWWDAQFARTWTGDQEPPDALIQESLEDAVAAIARDQERAGLDIISDGRVHGDNYAEQALYYYYRRLGYDLKGGYLGFPIYSRLHAGTLTGEVRRHGAIMVEQAKALKKATGKPTKVQYTGVQALTQATNDLHYKSSRDRAMAIAKAINEDIREVDALGVDFIQIDEFTWPYFFEDWAIEAFNAAVDGVKNAKIIAHVCWGNWGGTPAYYPDETAASGEIFDLTKRKAEATKATATGSIVPKAYEARLDVLNLESCGRRSDDLSGLHVMKNHPLPDNVSFWAGVIDVKSTITETADEVANRIRRLLEIVPADRLGVTTDCGLILLQRYIAQDKLHALVEGTKIVRAELAKAKQAA

41.7 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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