Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

Belongs to the DXR family.

401 amino acids

MQKRLTLLGSTGSIGDSTLDVVARHPDRFFVYALTAHRNGDKLVEQCLRFQPEVAVVGDADTAAKVAAKLRAAGCKTAVAYGPQALVDVSKSDGCDTVVAAIVGAAGLEPSLAAARAGKRILLANKEALVMSGSIFMDAVHDNGAILLPVDSEHNAIFQCLPRESALHGGVSKIILTASGGPFRTREPASLVDVTPDEACKHPNWVMGRKISVDSATMMNKGLEVIEAHWLFNLPGDRIDVLIHPQSVIHSLVSYADGSVLAQLGNPDMRTPIAHALAFPDRVDSGVGQLDLAQIAQLSFEKPDYTRFPCLALAMKALAEGGVASAALNAANEIAVEAFLTRRIGFMAIAQVVDAVLNSLPNREATSLADVVDADAAARRAAHAYIDGLPAGARLTERAVQ

42.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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