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znf830

Gene
ZNF830
Protein
Zinc finger protein 830
Organism
Homo sapiens
Length
372 amino acids
Function
May play a role in pre-mRNA splicing as component of the spliceosome (PubMed:25599396). Acts as an important regulator of the cell cycle that participates in the maintenance of genome integrity. During cell cycle progression in embryonic fibroblast, prevents replication fork collapse, double-strand break formation and cell cycle checkpoint activation. Controls mitotic cell cycle progression and cell survival in rapidly proliferating intestinal epithelium and embryonic stem cells. During the embryo preimplantation, controls different aspects of M phase. During early oocyte growth, plays a role in oocyte survival by preventing chromosomal breaks formation, activation of TP63 and reduction of transcription (By similarity).
Mass
41.999 kDa
Sequence
MASSASARTPAGKRVINQEELRRLMKEKQRLSTSRKRIESPFAKYNRLGQLSCALCNTPVKSELLWQTHVLGKQHREKVAELKGAKEASQGSSASSAPHSVKRKAPDADDQDVKRAKATLVPQVQPSTSAWTTNFDKIGKEFIRATPSKPSGLSLLPDYEDEEEEEEEEEGDGERKRGDASKPLSDAQGKEHSVSSSREVTSSVLPNDFFSTNPPKAPIIPHSGSIEKAEIHEKVVERRENTAEALPEGFFDDPEVDARVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEILTIKELQKKEEENADSDDEGELQDLLSQDWRVKGALL

Gene
Znf830
Protein
Zinc finger protein 830
Organism
Rattus norvegicus
Length
370 amino acids
Function
May play a role in pre-mRNA splicing as component of the spliceosome (By similarity). Acts as an important regulator of the cell cycle that participates in the maintenance of genome integrity. During cell cycle progression in embryonic fibroblast, prevents replication fork collapse, double-strand break formation and cell cycle checkpoint activation. Controls mitotic cell cycle progression and cell survival in rapidly proliferating intestinal epithelium and embryonic stem cells. During the embryo preimplantation, controls different aspects of M phase. During early oocyte growth, plays a role in oocyte survival by preventing chromosomal breaks formation, activation of TP63 and reduction of transcription (By similarity).
Mass
41.616 kDa
Sequence
MASSTSARTPAGKRVVNQEELRRLMKEKQRLSTNRKRIESPFAKYNRLGQLSCALCNTPVKSELLWQTHVLGKQHRERVAELKGAKGATQGPSAGTAPQPTKRKTTDVESQDAKKAKASVDQVQPSTSASSANFEKSGKEATRVASSKTGLGLLPDYEEEEEEEEEEELGGGEERRDSSKHLPDAQGREHSLASPRETTSNVLPNDPFNTNPPKAPLVPHSGSIEKAEIHEKVVERRENTAEALPEGFFDDPEVDAKVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEVLTIKELQKKEEENVDSDDEGELQDLLSQDWRVKGALL

Gene
Znf830
Protein
Zinc finger protein 830
Organism
Mus musculus
Length
363 amino acids
Function
May play a role in pre-mRNA splicing as component of the spliceosome (By similarity). Acts as an important regulator of the cell cycle that participates in the maintenance of genome integrity (PubMed:21191184, PubMed:23213458, PubMed:25168238, PubMed:15988037). During cell cycle progression in embryonic fibroblast, prevents replication fork collapse, double-strand break formation and cell cycle checkpoint activation (PubMed:21191184). Controls mitotic cell cycle progression and cell survival in rapidly proliferating intestinal epithelium and embryonic stem cells (PubMed:23213458). During the embryo preimplantation, controls different aspects of M phase (PubMed:15988037). During early oocyte growth, plays a role in oocyte survival by preventing chromosomal breaks formation, activation of TP63 and reduction of transcription (PubMed:25168238).
Mass
40.658 kDa
Sequence
MASSTSTRTPAGKRVVNQEELRRLMREKQRLSTNRKRIESPFAKYNRLGQLSCALCNTPVKSELLWQTHVLGKQHRERVAELKGAKGATQGPSTGTVPQATKRRATDVESQDAKKAKASAGPQVQPSTSASSANLDAARAAPSKPGLGLLPDYDDEEEEEEEGGGEERRDSSKHLPDAQGKEHSLASPRETTSNVLPNDPFNTNPPKAPLVPHSGSIEKAEIHEKVVERRENTAEALPEGFFDDPEVDAKVRKVDAPKDQMDKEWDEFQKAMRQVNTISEAIVAEEDEEGRLDRQIGEIDEQIECYRRVEKLRNRQDEIKNKLKEVLTIKELQKKEEENVDSDDEGELQDLLSQDWRVKGALL

Gene
znf830
Protein
Zinc finger protein 830
Organism
Xenopus tropicalis
Length
357 amino acids
Function
May act as an important regulator of the cell cycle that participates in the maintenance of genome integrity.
Mass
40.577 kDa
Sequence
MADAGKKKLVQQEELRRLMKAKQRRSCSKKRIESPLAKYNSLGHLLCVVCNIQIKSELLWPAHILGKQHKEKVAELKGSKANISSPSNKVQLHHIMKRKGSEPENQESKRIKGTEDQPTALKTKLPEGFFETEETSSAKHAAEKAPSLKLLAGDYEDDDEVEGEEYENVNEASTSLQKPAEIPLPPPTSSADRLPADFFESKMPLVSHSGSVLKADIQEKIVERKDNTAEALPEGFFDDPEADAKVRKVDAPKDQMDKEWEEFQKEIRQVNSVSDAIVAEEDEEGRLDRQIDEIDEQIECYRRVEHLRDLKDTLQDAKMEVLKSKSSKKWQEEIGSDDEETLPSLLYKNWRDKGAFL

Gene
znf830
Protein
Zinc finger protein 830
Organism
Xenopus laevis
Length
356 amino acids
Function
May act as an important regulator of the cell cycle that participates in the maintenance of genome integrity.
Mass
40.336 kDa
Sequence
MAVPGKKKLVAQEELRKLMKAKQRESSSKKRIESPLAKYNSLGHLSCVVCNSLIKSELLWPAHILGKQHKEKVAELKGTKATTSSPSNTIEYPRITKRKGSEPEKQESKRTKGSEDHPSASTTKLPEEFFEKEKTSSAGNAPSLKLLAGDYEDVDDDDAEEGEEYENAKEASSSLLKPAEIPLPPPTSSADNLPADFFENKMPLVSHSGSVLKADIQEKIVERKENTAEALPEGFFDDPEVDAKVRKVDAPKDQMDKEWEEFQKEIRQVNTVSEAIVAEEDEEGRLDRQIDEIDEQIQCYRRVEHLRDRKDTLQDAKMEVLKSKSNEKWQDEIGSDDEEKLPSLLYQNWREKGAFH

Gene
znf830
Protein
Zinc finger protein 830
Organism
Danio rerio
Length
326 amino acids
Function
May act as an important regulator of the cell cycle that participates in the maintenance of genome integrity.
Mass
36.219 kDa
Sequence
MAASRKGKAVKAVKQEDLRRLMQETRRDSGRQKRVESPFARYSGAGQLMCALCDAPVKNALLWQTHVLGKQHKDKLQELKSRTAPAHTPAPAHTPAHTPAAASSSSSTLKRAAEPPPAPGKRAKLQTGAGAGLGLLAGHYDDDDDDEGGAGERKTAPPTDSALPADFFDSGPAPAPPISHSGSVSKAEQQESQEPPENRPESLPEGFFDDPVRDAQVRQVDTPKDQLEREWEEFQKEMRQVNSASDAIVAEDDEEGRLERQMDEIEEQMQCLRRVEELRAKQETARSRRRSQRREEEPMQEEEPLEEEEELMHILTQDWRAKGALA