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yedS

Gene
yedS
Protein
Outer membrane protein YedS
Organism
Escherichia coli
Length
357 amino acids
Function
Forms pores that allow passive diffusion of small molecules across the outer membrane (By similarity). Plays a role in resistance to carbapenems; this carbapenem-resistant, noncarbapenemase-producing clinical isolate has a deletion in ompF and a mutated marR gene that does not induce expression of this protein. However if this gene is overexpressed, or if wild-type marR is introduced, this leads to decreased resistance to the carbapenem antibiotics ertapenem, imipenem and meropenem (PubMed:23318808).
Similarity
Belongs to the Gram-negative porin family.
Mass
39.714 kDa
Sequence
MKRKVLAMLVPALLVAGAANAAEIYNKDGNKVDFYGKMVGERIWSNTDDNNSENEDTSYARFGVKGESQITSELTGFGQFEYNLDASKPEGSNQEKTRLTFAGLKYNELGSFDYGRNYGVAYDAAAYTDMLVEWGGDSWASADNFMNGRTNGVATYRNSDFFGLVDGLNFAVQYQGKNSNRGVTKQNGDGYALSVDYNIEGFGFVGAYSKSDRTNEQAGDGYGDNAEVWSLAAKYDANNIYAAMMYGETRNMTVLANDHFANKTQNFEAVVQYQFDFGLRPSLGYVYSKGKDLYARDGHKGVDADRVNYIEVGTWYYFNKNMNVYTAYKFNLLDKDDAAITDAATDDQFAVGIVYQF

Gene
yedS
Protein
Putative outer membrane protein YedS
Organism
Escherichia coli (strain K12)
Length
161 amino acids
Similarity
Belongs to the Gram-negative porin family.
Mass
17.296 kDa
Sequence
MKRKVLAMLVPALLVAGAANAAEVYNKDGNKLDLYGKVVGLHYFSDDSGSDGDMSYARIGFKGETQIADQFTGYGQWEFNIGANGPESDKGNTATRLAFAGLGFGQNGTFDYGRNYGVVYDVEAWTDMLPEFGGDTYAGADNFMNGRANGVATYRNNGFFG