About Products Protein Database Contact

yafW

Gene
yafW
Protein
Antitoxin YafW
Organism
Escherichia coli (strain K12)
Length
105 amino acids
Function
Antitoxin component of a type IV toxin-antitoxin (TA) system. Antitoxin that counteracts the effect of cognate toxin YkfI (PubMed:14594833, PubMed:28257056). It does not seem to bind to the cognate toxin but instead induces toxin loss by an unknown mechanism (PubMed:14594833). Co-overexpression of toxin YkfI and antitoxin YafW leads to formation of elongated cells (PubMed:28257056).
Similarity
Belongs to the CbeA/YafW/YfjZ antitoxin family.
Mass
11.94 kDa
Sequence
MSNPTRGLQREITLRLGARLVQEGNRLHYLADRASITGKFSDIECRKLDETFPHFILQMESMLTTGELSPHHAHCVTLYHNDLTCEADTLGSCGYVYIAIYPTQR