xpt1

Gene

XPT1

Protein

3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose xylosylphosphotransferase

Organism

Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071)

Length

865 amino acids

Function

Xylosylphosphotransferase that is specific for UDP-xylose as a donor and mannose as an acceptor to form a xylose-alpha-1-phosphate-6-mannose linkage. Functions in the O-glycosylation of proteins en route through the secretory pathway (By similarity).

Similarity

Belongs to the XPT1 family.

Mass

99.891 kDa

Sequence

MLSTALSPSSPHADYNSYSSSLSPTSPRFHASSAPHGRRSPSPSRLESLLDAPLPSCRPSRSPRSRKIRDALARHIRPHLTPRTLTMLFLWMLSVWSIHHFFLPISSLSRLSNPRAEEHFLSTAFPPPPQRIGDDHLDSVDPRWRAYHPLPAPDPPFPRLRPTRFLPPQCLEQWFAEGETLCGAKELGEEEKLDATWLWVNGSDHRWRDSMIEWREKENVNSPERHFREQNELVHSMRSVLDALPGHLRTFHLILADYTFNYPEDLELVPFSIIPDLEKVASKSKGRRHPRDLPGTPPSFSNLTERVTPESISASLASHLQSEWRIVQTPTWLDFSRRDPSDPSHPFHPYSVSKAGERGQHYAEASYPTLRYASHWEVFHTPSVDRDGRQELMGEREWRENEWKKKALPTFNSMAIESRIGWLPGLADAIIALNDDFFLLRPHAVSDFHSPLYGSVIRFDHGYNQQVRPEVVKSHINDPGEIGGLYHANAILSQRFPHRLRPYFAHVPKVITRGLHHEASLMFKEALTESSTRRFREMKIGEGDVQMQWLLTSLRVERWREALLWTWVVANMGTISGSQDRWDDATRTAIKDMFGFTENDNDVVKIEVHRGERWTLEPGRMQKAFEQAGWEAPKATEFLFSSMDGTMPPLLKHGEDPAQNDRCMIDLNRCFGVFWTREEDILSTDMMKRLTFQYPECGDCMIMALVTASGTLGLNAFFPPKETTVTAPELAPGDGYPKFLPPPHLPLTPTWHEADFSLANILSTTALPGEQVDIRQYCMRLLSRYLYLDARSVSHFHMLKSAEHAQRVFKMIQDNPRVSILGMNDDIESDYDEVKRLMNEWFEMRWPRKAVWEREWDPVKDRYID

Protein

3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose xylosylphosphotransferase: XPT1

Gene

XPT1

Protein

3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose xylosylphosphotransferase

Organism

Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)

Length

864 amino acids

Function

Similarity

Belongs to the XPT1 family.

Mass

99.644 kDa

Sequence

MPPTALPPLRPPAQPYDSYSSSLSPSSPRFHPASAPHGRRAPSPSRLESLLDAPHAPARSPSRKIRSALSRHIRPHLTPRTLTPLLLWTLALWLVHHFLFPFSSPLAALSRPKAEQHFLSTTFPPPPQRLGDDRLDSVDPRWRAFHPLPPPEPPFPRLRPTRFLPPQCLEQWFADGETLCGAKEMGEEETLDATWLWVNGSDHRWRDSMAEWREKENVNSPERHFREQNELVHSMRSVLDALPGHLRTFHLILADYPFNYPEDLDLVPPSIIPDLEVAASKGGQGRRHPRELARAPASVSNLTERLTPESISPSLARHLQSEWRILQTPTWLDFSRRDPSDPSHPFHPYSVSKAGEMRQHYAEASYPTLRYASHWEVFHIPSVDRDGREELMGEREWRENEWKKKALPSFNSMAIESRIGWLPGLADAIIALNDDFFLLRPHAVSDFHSPLYGSVIRFEHSYNQQVKPDVEKNHINDPGEMGGLYHANALLSRRFPHRLRPYFAHVPKVITRGLHHEASLMFQEALTLSSTRKFREMKIGEGDVQMQWLLTSLRVERWREALLWTWVVANMGTLSGSHDRWDSDTRSAIKHLFGFTEDDDDVVKIEVHRGERWTLEPGRMQKVFHQAGWEAPKATEFLFSSMDGIMPPLLRSGEDPSQNDRCIIDLNRCFGVFWTRQEDVLSADMMKRLTFQYPECGDCMIMALVTASGTLGLNAFFPPKETTITAPELGPGDAYPKYLPPPHLPLTPTWHEADYSLSNILSTTALPGEQVDIRQYCMRLLSRYLYLDAKSVSHFHMMKSAEHAKRVFKMIQDNPKVSILGMNDDIESDYDEVKRLMNEWFEMRWPRKAVWERDWDPVKDRYHD

Protein

3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose xylosylphosphotransferase: XPT1

Gene

XPT1

Protein

3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose xylosylphosphotransferase

Organism

Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)

Length

864 amino acids

Function

Similarity

Belongs to the XPT1 family.

Mass

99.644 kDa

Sequence

Protein

3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose xylosylphosphotransferase: XPT1

Gene

XPT1

Protein

3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose xylosylphosphotransferase

Organism

Cryptococcus neoformans var. grubii

Length

864 amino acids

Function

Similarity

Belongs to the XPT1 family.

Mass

99.527 kDa

Sequence

MPSTALSPPSRPPAQSYDSYSSSLSPSSPRFHAAAGSHGRRSPSPSRLESLLDGPHVPPRSPSRKIRSALSRHIRPHITPRTLTPVFLWTLALWLIHHFLFPLSSPFAKLAKPKAEEHFLSTTFPPPAQRLGDDRLDSVDPRWRAYHPLPAPEPPFPRLRPTRFLPPQCLEQWFAEGETLCGAKEMGEEETLDATWLWVNGSDHRWRDSMVEWREKENVNSPERHYREQNELVHSMRSVLDALPGHLRTFHLILADYPFNYPEDLELVPSSIIPDLEVAASKSKGRRHPRELPGAPASLANLTERVTPESISPTLASHLQSEWRILQTPTWLDFSRRDPSDPSHPFHPYSVSKAGEIRQHYAEASYPTLRYASHWEVFHIPSVDRDGRQELMGEREWRENEWKKKALPSFNSMAIESRIGWLPGLADAIIALNDDFFLLRPHAVSDFHSPLYGSVIRFEHGYNQQVKPDVEKNHINDPGEMGGLYHANALLSRRFPRRLRPYFAHVPKVITRGLHHEASLMFQEALTESSTRRFREMKIGEGDVQMQWLLTSLRVERWREALLWTWTVANMGTLGGSQDHWDNDTRRAIKNLFGFTENDDDVVKIEVHRGERWTLEPGRMQRVFRQAGWEAPKATEFLFSSMDGIMPPLLRSGEDPAQNDRCIIDLNRCFGLFWTREEDVLSSDMMKRLTFQYPECGDCMIMALVTASGTLGLNAFFPPKETTITAPELGPGDAYPKFLPPPHLPLTPTWHEADFSLANILSTTALPGEQVDIRQYCMRLLSRYLYLDAKSVSHFHMMKSAEHARRVFRMIQGDPKVSILGMNDDIESDYDEVRGLMNEWFEMRWPRKAVWERDWDPVKDRYND

Protein

3-O-alpha-D-mannopyranosyl-alpha-D-mannopyranose xylosylphosphotransferase: XPT1

Gene

XPT1

Protein

Xanthine phosphoribosyltransferase 1

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

209 amino acids

Function

May act as a xanthine phosphoribosyltransferase involved in the synthesis of purine nucleotides. Such activity is however unclear in vivo.

Mass

23.671 kDa

Sequence

MAENERMYISYNNIHKLCQGVAKHILARNERPDIIIAITGGGMIPARIIRSFLKTKGQKNIPIQAIGLSLYEDLGLDNSVETIGKEVIRTQWLDFGALNQHFDSLIGKKVLIVDEVDDTRTTLHYAVSELEKEIAEQQKVLNRMSEETVISIFVLHNKDKPKRAGLPDSMMNSGRYIAAQTVPDKWLCYPWDAEDIEEHTMLAKAQGHD

Protein

Xanthine phosphoribosyltransferase 1: XPT1

Gene

xpt1

Protein

Xanthine phosphoribosyltransferase 1

Organism

Clostridium botulinum (strain ATCC 19397 / Type A)

Length

190 amino acids

Function

Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.

Similarity

Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.

Mass

21.279 kDa

Sequence

MEKLQNRILQEGHALSETVLKVDSFLNHQVDPDLMYEIGTYFKNYFKEHKITKVFTIESSGIAPAVMTAMQMNLPMVILKKQASKILNGDVYQTTVHSFTKGLDYELTLSKKYIAKEDNILIIDDFLANGEAALGAARLVKEAGAKVAGMGIVIEKSFQPGRKMLEDKGYDVYSLARIAKLQKGLIEFVK

Protein

Xanthine phosphoribosyltransferase 1: xpt1

Gene

xpt1

Protein

Xanthine phosphoribosyltransferase 1

Organism

Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A)

Length

190 amino acids

Function

Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.

Similarity

Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.

Mass

21.279 kDa

Sequence

MEKLQNRILQEGHALSETVLKVDSFLNHQVDPDLMYEIGTYFKNYFKEHKITKVFTIESSGIAPAVMTAMQMNLPMVILKKQASKILNGDVYQTTVHSFTKGLDYELTLSKKYIAKEDNILIIDDFLANGEAALGAARLVKEAGAKVAGMGIVIEKSFQPGRKMLEDKGYDVYSLARIAKLQKGLIEFVK

Protein

Xanthine phosphoribosyltransferase 1: xpt1

Gene

xpt1

Protein

Xanthine phosphoribosyltransferase 1

Organism

Clostridium botulinum (strain Langeland / NCTC 10281 / Type F)

Length

190 amino acids

Function

Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.

Similarity

Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.

Mass

21.367 kDa

Sequence

MEKLQNRILQEGHALSETVLKVDSFLNHQVDPDLMYEIGTYFKNYFKEHKITKIFTIESSGIAPAVMTAMQMNLPMVILKKQASKILNGDVYQTTVHSFTKGLDYELTLSKKYINKEDNILIIDDFLANGEAALGAARLVQESGAKVAGMGIVIEKSFQPGRKMLEEKGYDVYSLARIAKLEKGLIEFVK

Protein

Xanthine phosphoribosyltransferase 1: xpt1

Gene

xpt1

Protein

Xanthine phosphoribosyltransferase 1

Organism

Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A)

Length

190 amino acids

Function

Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.

Similarity

Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.

Mass

21.464 kDa

Sequence

MEALKEKILKEGKVREGNILKVDCFLNHQMDIKFLNEVGKEFRKRFEGEKVDKILTIEASGIAIAGIASQYFDYVPVVFAKKTESLNLDKDVYESNVHSFTKKKDYKVRVGKQFLNKGERVLIIDDFLAQGCATKGMIDLVEQAGAELVGIGIVIEKGFQDGRKVLEDLGVRVESLAIIDKLEDNKVYFK

Protein

Xanthine phosphoribosyltransferase 1: xpt1

Gene

xpt1

Protein

Xanthine phosphoribosyltransferase 1

Organism

Clostridium perfringens (strain 13 / Type A)

Length

190 amino acids

Function

Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.

Similarity

Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.

Mass

21.464 kDa

Sequence

MEALKEKILKEGKVREGNILKVDCFLNHQMDIKFLNEVGKEFRKRFEGEKVDKILTIEASGIAIAGIASQYFDYVPVVFAKKTESLNLDKDVYESNVHSFTKKKDYKVRVGKQFLNKGERVLIIDDFLAQGCATKGMIDLVEQAGAELVGIGIVIEKGFQDGRKVLEDLGVRVESLAIIDKLEDNKVYFK

Protein

Xanthine phosphoribosyltransferase 1: xpt1

Gene

xpt1

Protein

Xanthine phosphoribosyltransferase 1

Organism

Clostridium perfringens (strain SM101 / Type A)

Length

190 amino acids

Function

Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.

Similarity

Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.

Mass

21.464 kDa

Sequence

MEALKEKILKEGKVREGNILKVDCFLNHQMDIKFLNEVGKEFRKRFEGEKVDKILTIEASGIAIAGIASQYFDYVPVVFAKKTESLNLDKDVYESNVHSFTKKKDYKVRVGKQFLNKGERVLIIDDFLAQGCATKGMIDLVEQAGAELVGIGIVIEKGFQDGRKVLEDLGVRVESLAIIDKLEDNKVYFK

Protein

Xanthine phosphoribosyltransferase 1: xpt1