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xpf

Gene
xpf
Protein
3'-flap repair endonuclease Xpf
Organism
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Length
233 amino acids
Function
A structure-specific endonuclease, cleaves 5' of ds/ssDNA interfaces in 3' flap structures, although it also cuts bubble, Y-DNA structures and mobile and immobile Holliday junctions. Cuts preferentially after pyrimidines, may continue to progressively cleave substrate upstream of the initial cleavage, at least in vitro. May be involved in nucleotide excision repair.
Mass
26.683 kDa
Sequence
MVIRIYADDREKASGIPELLKELGITVIFSQLTVADYVITDDVAVERKSVNDLVNSVFDKRFFDQISRLSEVYRFPILLVEGDINDIRKITEKWRAINNALISATIDYDVKVFYSRDKKDTAEVLKKIAEKFQFGENKSNRISLHNKAKLESVSDIQLYIVESFPNVGSILAERLLLKFGTIQNICNASISELEKALGSRKKAEDIYKILRTHYSKTNLDNDSKKTTSLFDFL

Gene
xpf
Protein
Positive control factor
Organism
Bacillus subtilis (strain 168)
Length
169 amino acids
Function
Positive regulatory protein that acts at the late promoter PL.
Mass
20.091 kDa
Sequence
MQDLLFEYKRTLKQTRIQYKPLAEADESVLSAEELKDKKIIRNMITDLEYVTEWLEKGRQPGIRRAIDRRDVYQRLMIKDPRIIESFSSAMMFEPDGQVSEEDRDRIREALALLTDREKEMFLLHKVECFSYERIADLLGVKKSTVQTTIKRASLKMQRQQEEMNRSLA