xkr8

XK-related protein 8

404 amino acids

Promotes phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment (By similarity).

Belongs to the XK family.

46.385 kDa

MEGATFSKYSWIDFVFSVIGACTFLVDWGSDVWLAAEFYRRGDVTWFWVLVGLMALSSFVVQTFSWFWFQYDRELPGFRAQTEAAAVLLGDRAKLSCAVHVLQLGFLCRHISAIRQGFRVWWRKEKGSEYAIYQTHDLSMLRLIETFCESAPQLTLMIYVMLHTHKARAVQFVSIAASTTSIAWMVVDYHRSLRSFLPDKAKQGWGSSLIYFLWNLLLIAPRVAALALCASVLSGYMAAHFLMLWSAFALWAWRQGTHFMDSVAGEWLYRATVGLIWYFSWFNVKDGQTRSRSAIYHSFISTDGAILLATWWCHRDPVQTQSYALALLIALPLFHFLGLLFKALYYCCFHPKLWRPPARDPGLPNDLPDAQVSMRDFPIQDGGLSPKLLNKRMAGQVARFYSDE

xkr8

XK-related protein 8

404 amino acids

Promotes phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment (By similarity).

Belongs to the XK family.

46.566 kDa

MEQPSIYNYSWVDFVFSVIGVFTFFVDWGADVWVATEFYRRGDFFWFGVLVGLMVLSSVLVQMFSWFWLQYDRGLPDLQTGGGTVLFGDRLRLSCLLHVLQLGFLCRHISAIRQGFRVWWRKEEGSEYAFYLSHDLSMLRLIETFSESAPQLTLMIYVMLRTQRARAVQFVSVAASTTSIAWMVVDYHRCLRSFLPDKARQGWASSLIYFLWNLLLIAPRVAALALFASVVGGYLGLHLLLLWLVFVTWAWLQRTHFMDSPGGEWLYRATVGIIWYFSWFNVAEGRTRGRSAIYHAFITADGAILLVTWWCCREPVQAEPYALALLLTLLLSYLLGLLFKSLYYCCFHPTLWRPPAREPGLPDDLPDADVTFRHLSIQDGAPASRPLNRRMALHAADFYSARTS

Xkr8

XK-related protein 8

401 amino acids

Promotes phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Has no effect on calcium-induced exposure of phosphatidylserine. Activated upon caspase cleavage, suggesting that it does not act prior the onset of apoptosis.

Belongs to the XK family.

45.563 kDa

MPLSVHHHVALDVVVGLVSILSFLLDLVADLWAVVQYVLLGRYLWAALVLVLLGQASVLLQLFSWLWLTADPTELHHSQLSRPFLALLHLLQLGYLYRCLHGMHQGLSMCYQEMPSECDLAYADFLSLDISMLKLFESFLEATPQLTLVLAIVLQNGQAEYYQWFGISSSFLGISWALLDYHRSLRTCLPSKPRLGRSSSAIYFLWNLLLLGPRICAIALFSAVFPYYVALHFFSLWLVLLFWIWLQGTNFMPDSKGEWLYRVTMALILYFSWFNVSGGRTRGRAVIHLIFIFSDSVLLVTTSWVTHGTWLPSGISLLMWVTIGGACFFLGLALRVIYYLWLHPSCSWDPDLVDGTLGLLSPHRPPKLIYNRRATLLAENFFAKAKARAVLTEEVQLNGVL

XKR8

XK-related protein 8

395 amino acids

Promotes phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Has no effect on calcium-induced exposure of phosphatidylserine. Activated upon caspase cleavage, suggesting that it does not act prior the onset of apoptosis.

Belongs to the XK family.

44.655 kDa

MPWSSRGALLRDLVLGVLGTAAFLLDLGTDLWAAVQYALGGRYLWAALVLALLGLASVALQLFSWLWLRADPAGLHGSQPPRRCLALLHLLQLGYLYRCVQELRQGLLVWQQEEPSEFDLAYADFLALDISMLRLFETFLETAPQLTLVLAIMLQSGRAEYYQWVGICTSFLGISWALLDYHRALRTCLPSKPLLGLGSSVIYFLWNLLLLWPRVLAVALFSALFPSYVALHFLGLWLVLLLWVWLQGTDFMPDPSSEWLYRVTVATILYFSWFNVAEGRTRGRAIIHFAFLLSDSILLVATWVTHSSWLPSGIPLQLWLPVGCGCFFLGLALRLVYYHWLHPSCCWKPDPDQVDGARSLLSPEGYQLPQNRRMTHLAQKFFPKAKDEAASPVKG

XKR8

XK-related protein 8

395 amino acids

Promotes phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment. Has no effect on calcium-induced exposure of phosphatidylserine. Activated upon caspase cleavage, suggesting that it does not act prior the onset of apoptosis (By similarity).

Belongs to the XK family.

44.667 kDa

MPWSSRGALLRDLVLGVLGTAAFLLDLGTDLWAAVQYALGGRYLWAALVLALLGLASVALQLFSWLWLRADPAGLHGSQPPRRCLALLHLLQLGYLYRCVQELRQGLLVWQQEEPSEFDLAYADFLALDISMLRLFETFLETAPQLTLVLAIMLQSGRAEYYQWVGICTSFLGISWALLDYHRALRTCLPSRPLLGLGSSVIYFLWNLLLLWPRVLAVALFSALFPSYVALHFLGLWLVLLLWVWLQGTDFMPDPSSEWLYQVTVATILYFSWFNVAEGRTRGRAIIHFAFLLSDSILLVATWVTHSSWLPSGIPLQLWLPVGCGCFFLGLALRLVYYHWLHPSCCWKPDPDQVDGARSLLSPEGYQLPQNRRMTHLAQNFFPKAKDEAALPVKG