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whiB7

Gene
whiB7
Protein
Transcriptional regulator WhiB7
Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length
103 amino acids
Function
Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA (By similarity). Participates in maintaining a reduced cytoplasmic (MSH/MSSM) environment under normal growth conditions and directly or indirectly controls the concentration of mycothiol (MSH + MSSM).
Similarity
Belongs to the WhiB family.
Mass
10.95 kDa
Sequence
MSIAMTAPTTGVAPMTCETRLPAVPCHVGDPDLWFAENPGDLERAKALCAGCPIRVQCLTAALERQEPWGVWGGEILDRGSIVARKRPRGRPRKDSGGNPAAA

Gene
whiB7
Protein
Probable transcriptional regulator WhiB7
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
92 amino acids
Function
The apo- but not holo-form probably binds DNA (By similarity). Acts as a transcriptional regulator. Probably redox-responsive. Upon overproduction at least 10 other genes are up-regulated, among them are Rv1258c, Rv1988, Rv2301, Rv2416c, Rv2725c and whiB7 itself. Probably redox-responsive. The apo-form has been shown to act as a protein disulfide reductase.
Similarity
Belongs to the WhiB family.
Mass
10.139 kDa
Sequence
MSVLTVPRQTPRQRLPVLPCHVGDPDLWFADTPAGLEVAKTLCVSCPIRRQCLAAALQRAEPWGVWGGEIFDQGSIVSHKRPRGRPRKDAVA

Gene
whiB7
Protein
Probable transcriptional regulator WhiB7
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
92 amino acids
Function
Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA (By similarity).
Similarity
Belongs to the WhiB family.
Mass
10.139 kDa
Sequence
MSVLTVPRQTPRQRLPVLPCHVGDPDLWFADTPAGLEVAKTLCVSCPIRRQCLAAALQRAEPWGVWGGEIFDQGSIVSHKRPRGRPRKDAVA