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whiB1

Gene
whiB1
Protein
Transcriptional regulator WhiB1
Organism
Bifidobacterium longum (strain NCC 2705)
Length
92 amino acids
Function
Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA (By similarity).
Similarity
Belongs to the WhiB family.
Mass
10.406 kDa
Sequence
MSSAFDWRAKAACRDKDPELFFPVGNTGAAYQQIEEAKAVCRTCKVIDACLKCALDTNQDYGVWGGLSEDERRALKRRAMRARRSQAMQMQI

Gene
whiB1
Protein
Transcriptional regulator WhiB1
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
84 amino acids
Function
Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA (By similarity).
Similarity
Belongs to the WhiB family.
Mass
9.319 kDa
Sequence
MDWRHKAVCRDEDPELFFPVGNSGPALAQIADAKLVCNRCPVTTECLSWALNTGQDSGVWGGMSEDERRALKRRNARTKARTGV

Gene
whiB1
Protein
Transcriptional regulator WhiB1
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
84 amino acids
Function
Acts as a transcriptional repressor, inhibiting expression in vitro. Probably redox-responsive. The apo- but not holo-form binds to its own promoter as well as that of groEL2. Oxidized apo-form and nitrosylated holo-form also bind DNA. The apo-form has been shown to act as a protein disulfide reductase (PubMed:17157031) (PubMed:19016840), but also not to act as a protein disulfide reductase (PubMed:20929442).
Similarity
Belongs to the WhiB family.
Mass
9.319 kDa
Sequence
MDWRHKAVCRDEDPELFFPVGNSGPALAQIADAKLVCNRCPVTTECLSWALNTGQDSGVWGGMSEDERRALKRRNARTKARTGV