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wdr-48

Gene
wdr-48
Protein
WD repeat-containing protein 48 homolog
Organism
Caenorhabditis briggsae
Length
691 amino acids
Function
Together with wdr-20, binds to and stimulates the activity of the deubiquitinating enzyme usp-46, leading to deubiquitination and stabilization of the glr-1 glutamate receptor.
Similarity
Belongs to the WD repeat WDR48 family.
Mass
77.852 kDa
Sequence
MSGASNTSQSGSKKKLSFIIRDEQEPLHRSAVSALQYDALHSRLFTGGSDTIIRTWSVPQHKDAFSARGGVRSAGKNSPVQYQSSLERHTDWVTDMVLCGNGKLLVSSSNDTTVKVWSIERDNKHGYLDSLNLHTDYVSCLAYAPLAEKVVSASFDRNIFVYDVNSNFNNFRVLVNNLLGCKNSIYSLATTPNLSHCLFFSPHQQIRMFDPRTNDKPMKMRGHSDNVRALLLNDDGTRALSAGSDGTIRLWDIGMQKNIATGIAHEEGVWTIQVDASFKFVYSGGRDRYVLKSPVNDLSKFQVLFKEEAPVKKLLLSEKENPSSIWVGTWKSDIKRWSLNSANQNSNGGDEEGVSSFSTYYTTCKPRSSSPPPGITAPKHIQRLTDARELQNTPELMISGAPAINKYKILNDKRHVLTSDTEDNVALYDVLAGKKVKEYGKRALENVFEEKSKTVYVPSWFIVDSKSGMLQITLDELDVFSSWLTTKDAGFDDSDKETKVNYGGMMLRSLFERWPPCKLATAEAGESDEVQKATSHYYTLPEHTPFIVCEGNGRPLFRLLVGDAGNEFESGELAQCVPPWVTDMIERNVLPKFNKMPFYLLPHPSTNSKQPKKDRLSATEMLLVKKVMEHVYEKVLGNVDANTVPLNQIHTKIEMYCNDQKLEPETDLRTVKHFYWKQSGELLLYYRPVKN

Gene
wdr-48
Protein
WD repeat-containing protein 48 homolog
Organism
Caenorhabditis elegans
Length
683 amino acids
Function
Together with wdr-20, binds to and stimulates the activity of the deubiquitinating enzyme usp-46, leading to deubiquitination and stabilization of the glr-1 glutamate receptor.
Similarity
Belongs to the WD repeat WDR48 family.
Mass
76.674 kDa
Sequence
MSSCVNTSQTGPKKKISFIIRDEHEYSNRSAVSALQYDAQNGRLFTGGSDTIIRTWSVPHHKDAFSARGGVRSPGKNSPVQYQGSLEQHTDWVNDMILCGHGKILISASNDTTVKVWNIERDNKHGFIDCIRTHKDYVSCLAYAPIVEKAVSASFDHNIFVYDINANFKTVNNLIGCKDSIYSLATTPNLSLVLGAGTEKCIRLFDPRTNEKIMKLRGHTDNVRALVVNDDGTRALSAGSDATIRLWDIGQQRCIATCIAHEEGVWTLQVDSSFTTVYSAGKDKMVVKTPLYDFTKSQLLFKEEAPVKKLLLSEKDNPVSLWVGTWKSDIKRWSIRPSAQLSIGGDEDGPSTSNANHSVSASSSPPVTFKYIRVKDQKGQQSTPELVIPGAPAIKKHAMLSDKRHVLTRDSDGNVALYDVLAARKIKDYGKRIFEEVVDENSRQVYIPSWFVVDSKSGMLQITLDELDALSSWLSSKDAGFDDNDRETKLNYGGMMLRSLFERWPPCKMTNVDAADADDVQKATLNFISLPEHTPLIICEGNGRPLYRLLVGDAGKEFEANELAQIAPMWVIDAIERNQLPKFNKMPFYLLPHPSTNPKQPKKDRLSATEMLQVKKVMEHVYEKILSTNDDITVGSIPLNQIHTKMEMYCNDQRLEPDMDLRTVKHLYWKQSGELLLHYKPVK