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wdr-4

Gene
wdr-4
Protein
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit
Organism
Caenorhabditis elegans
Length
388 amino acids
Function
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
Similarity
Belongs to the WD repeat TRM82 family.
Mass
43.639 kDa
Sequence
MSFITAFRERVFIASGDLIRTFRISEETELKNFISWSKINPERIQKPSFDIEKELKAVEKRVILCLAHSNVLTTHGRRLVAVGTNEKQIHVFEYFVNDKGDIVTAEHIVTSVVPKAPTAIVFDKEDAYVVVGDRAGDVHRFSVLNGSAIEMAGAISMILDVAFSPDGKRLLMADRDEKVRALRYPATSVIDSFFLGHTEYVKTLAVQDNDSLWSSGGDKNLYNWSIAKCSAPRRTLDLSQFDAPIRKISINLQHKKIAVIFEKIETVVIVDLNQESLQTTSVSIVGESQCLDIASTKDYFAVLGRSTVHLIDLNNMEQKFVPIDEELTITLTSTNDAIDNLFKNVTHNNQQEYEKRKADKFEQIEKKKRRLNEDINGDDGEGPGPSNS

Gene
wdr-4
Protein
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit
Organism
Caenorhabditis briggsae
Length
379 amino acids
Function
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
Similarity
Belongs to the WD repeat TRM82 family.
Mass
42.655 kDa
Sequence
MSFITAFGDRVFVASGDLIRTFRIGDDEGMTPLISWSELNPERIQKPSFEAEKDLKAVDKRVILCLAHSNMIAAHGRRLVAVGTNEKQIHVFEYFIDNNYKIVKAEHIVTSVVPKAPTAIVFDREDAYVVVGDRSGDVHRFSVLNGSAIEMAGAISMILDVAFSPDGKRLLMADRDEKVRAMRYPSTYVIDAYCLGHTEYVKTLAIQDNDTVWSSGGDKNLHMWSITNCSKPRRTIDLSEWDAPVRKISINVAHKKIAVLFEKKDKMIVVDLETDPAATQSVTILNESECLDVTSTGHYFIVLGRSTITVINLLTMLQATFPIDDELNAVLSATKDAVDNLFKNVTHNNQLEYEKRKAEKFEQIEQKRRRLNNQEPSTS