wdr-4

Gene

wdr-4

Protein

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit

Organism

Caenorhabditis elegans

Length

388 amino acids

Function

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Similarity

Belongs to the WD repeat TRM82 family.

Mass

43.639 kDa

Sequence

MSFITAFRERVFIASGDLIRTFRISEETELKNFISWSKINPERIQKPSFDIEKELKAVEKRVILCLAHSNVLTTHGRRLVAVGTNEKQIHVFEYFVNDKGDIVTAEHIVTSVVPKAPTAIVFDKEDAYVVVGDRAGDVHRFSVLNGSAIEMAGAISMILDVAFSPDGKRLLMADRDEKVRALRYPATSVIDSFFLGHTEYVKTLAVQDNDSLWSSGGDKNLYNWSIAKCSAPRRTLDLSQFDAPIRKISINLQHKKIAVIFEKIETVVIVDLNQESLQTTSVSIVGESQCLDIASTKDYFAVLGRSTVHLIDLNNMEQKFVPIDEELTITLTSTNDAIDNLFKNVTHNNQQEYEKRKADKFEQIEKKKRRLNEDINGDDGEGPGPSNS

Protein

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit: wdr-4

Gene

wdr-4

Protein

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit

Organism

Caenorhabditis briggsae

Length

379 amino acids

Function

Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Similarity

Belongs to the WD repeat TRM82 family.

Mass

42.655 kDa

Sequence

MSFITAFGDRVFVASGDLIRTFRIGDDEGMTPLISWSELNPERIQKPSFEAEKDLKAVDKRVILCLAHSNMIAAHGRRLVAVGTNEKQIHVFEYFIDNNYKIVKAEHIVTSVVPKAPTAIVFDREDAYVVVGDRSGDVHRFSVLNGSAIEMAGAISMILDVAFSPDGKRLLMADRDEKVRAMRYPSTYVIDAYCLGHTEYVKTLAIQDNDTVWSSGGDKNLHMWSITNCSKPRRTIDLSEWDAPVRKISINVAHKKIAVLFEKKDKMIVVDLETDPAATQSVTILNESECLDVTSTGHYFIVLGRSTITVINLLTMLQATFPIDDELNAVLSATKDAVDNLFKNVTHNNQLEYEKRKAEKFEQIEQKRRRLNNQEPSTS

Protein

tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit: wdr-4