wdr-20

Gene

wdr-20

Protein

WD repeat-containing protein 20 homolog

Organism

Caenorhabditis elegans

Length

768 amino acids

Function

Together with wdr-48, binds to and stimulates the activity of the deubiquitinating enzyme usp-46, leading to deubiquitination and stabilization of the glr-1 glutamate receptor.

Mass

83.741 kDa

Sequence

MHQHMLGPSTSLGGTNNSALQSSVLSEGVLLSHSQPTREEIKKNFETREGVYRSVPSAEFSRPRPLPQYHMPPGIASAAASQIAAAGSTVRVSFLNGAEKSVESPEAVAPTSSTYEHHKNEPNGARIDMVDEAQADKICFNVGKELYVFSYRGTQTETDLSRPIDKRVYKGTSPTYHAFNQESAKNGSCQLLIGFTLGQLQIIDPLEKSSSSPFSRLYNEDRYIEKTSVTCIRWLPGDSNIFLASYVSGNLYVYDQRISAASSNNNGSSQPPPWTIHKEGDKFAIHTWKGKVQRNPVTRWQIGEGSIHQFSFSGSDGKMMATVSHDGFLRIFNYHAQELLAVMKSYFGGLLTLSWSPDAKLIATGGEDDLLTVYSVAEKRVVCRGQAHKSWVSQVKFDPYLCTTEEDLENNGIAMTSTFDDVAKDFSIRSGPVPSTSADLNSGVMNATSTFSRCSLASFNTINGAPAGNSVRYRIGSVGHDTFLCLWDITEDMLNQGNIRRHRNSTIIAPMTTLEVQTNSLVGRLEDLQEVSPGGAGVNASSDSQSITNNHTTPRPEKQKKKKFTKRLGFSKFTSGSSSATSNPVGGHKIGTLMNGASVNSESSKKQNPGLISQISCCNETRMLGSKFCPGIRDVPMIEPLMCKKVSHDRLTVLEFREDCVVTACQEGYICTWGRPGRYQPKRDCINSPGTASPESGQKPSGSTSAMTSSYGYGSDALNGVPPSRSSSTYSNSEQQLRSPNITSPSYRVSAASTSVYHRPTYAWQNAN

Protein

WD repeat-containing protein 20 homolog: wdr-20