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wc-2

Gene
wc-2
Protein
White collar 2 protein
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Length
530 amino acids
Function
May function as a transcription factor involved in light regulation. Binds and affects blue light regulation of the al-3 gene. Wc-1 and wc-2 interact via homologous PAS domains, bind to promoters of light regulated genes such as frq, and activate transcription. May bind directly to frq.
Mass
56.895 kDa
Sequence
MSHGQPPPGSSMYGFGAMGMGSGMGSGMGSGMGTGMGTGMGTGMSASQMTSDPQDMMSLLDTSVFPGFDGMSMSLDVGDSMSNPFTPVSVPPPLPAGNAGPSHVGVCGGHGAPDQLFSPDDLIATSMSSAGPMIATPTTTTSGPSGGPSSGGGSTLTEFTKRRNWPAKVVEELQDWEHILDANGRIKHVSPSVEPLTGYKPPEIIDLFLRDLIHPDDVGVFTAELNEAIATGSQLRLFYRFRKKDGNWTIFETVGHAHIAAAKFAPNPQNQSPFCQAVFMMARPYPTKNAGLLDSFLEHKIENERLKRRIAELRREEQEEQEESHRTWRMSQEGRSDVTPSDDTATQMGMTPFYIPMNAQADVMMPPPSQPASSLNIALTRENLEGIAGSRPDSIREKMLRYEGNHADTIEMLTGLKYQEGERSHGITTGNASPTLIKGDAGIAIPLDRDPRTGEKKKKIKVAEEYVCTDCGTLDSPEWRKGPSGPKTLCNACGLRWAKKEKKKNANNNNNGGGIGGHNDIHTPMGDHMG