Protein
Fatty acyl-CoA reductase wat
Organism
Drosophila melanogaster
Function
Catalyzes the reduction of saturated fatty acyl-CoA to fatty alcohols. The preferred substrates are C24:0 and C26:0. Necessary for the final stages of tracheal maturation, to facilitate the transition from water-filled to gas-filled tubes. May help to maintain the integrity of the outer hydrophobic envelope of the trachea.
Similarity
Belongs to the fatty acyl-CoA reductase family.
Sequence
MDDPKIMNIMNGMKSLEDHCQLISDVKDESPMQMFYKDKGVFLTGGTGFFGKIIIEKLLRVTEVGQIYLLIRTKKGKDAFARIEDLFNDPVFAKMKQVNPKYRCQITIISGDCSLPGLGISADERETIMENVNIVLHSAATVRFDEKLKMAIAINVHGTKEIIKLAKEIVNLKALVHVSTAFAHCNMRHIQERFYSGTMSGENAFKLSECLDEHTLNTLTPTIIKGYPNTYTFTKVLAENVVQQSAQNLPVTIFRPGIVITTYREPVTGWIDNMYGPCGVIVGIGSGVLRVFTGDMDNKAHIVPVDMCVNALLASAWDIARNKYETPPIYNYVPDAENMVTWRRYMEDGFEYGCDIPMRKSIWYPRFTIVPHMWQYHILCFLYHTLPALVMDAIMVIIGKKPRMMKIYRKIHKLSNVLKYFSSNEFRFDNDNVRKLTEKLDDRDKRLFAFDMRDLDWTNLFRVSLYGLRLYVVKDDPSNIPESIKRYERLKVLHYTTLAVFYALAAWALYALLKLFL