Protein
Transcription factor vrtR1
Organism
Penicillium aethiopicum
Function
Probable transcription factor that regulates expression of the gene cluster that mediates the biosynthesis of viridicatumtoxin, a tetracycline-like fungal meroterpenoid with a unique, fused spirobicyclic ring system (PubMed:20534346).
Sequence
MEDTTETTETTDTTAVSRLVPLAPAPARAPSMDAVNGSFDSELTTARRFNCQSCVRKKIKCNRAVPTCASCSKAKLHCVYQSRPPRKRKRSRGEEDVYERLAQYERILHDHNLLQAAAASTPSGRDTETSAISTRAPTPVLPDAQTHTKAGKVLLSTDGRSRYIDNVLLLDAGEGDLCELPESEQEDYNHDETSPDESTPTGLLGALAAHTISGAIIGNTQSLTNLHPTYEQAAKLWQAYVKNVEPLCKILHVPTVAKMFDTVSKQPAAVSKNDECLMFVIYYFAVFSMSDDECLHEFNYPRAQLLSRYQTTVIQALVNASWLKTTAMPVLQAYTLFLIALRTQIDSHTFWILTGIAVRLAQRMGLHRDGESLGLPPFEVQMRRRLFWQLLPLDSYAGQTSGTGISISPSSWDTKQPLNINDDQIFPGMTQPPCEQRGASEMIFCLSRMELSNFYIRTGVKLKEHGDTIQFRDAEDIERLIDEVEDLIETKFLRYCDILNPLHFLTTGIVRSAIDAVRLRARMPLLKQQTITDAQRRRLCALAEKVLDTNSTIFSNPSTQNFRWQMQAFFLWDALLCILRNIAEVGFYSPSELAAAWSKVANVYANHDELVKARRTLYVTIAKVTLKAWLANPPRDSSPQPAFITALLTQHEPKGINQQQNSVLSDDKAADGASLFDEFFDNMNGTDLDINNAFNLDSSSDWLFWDQICRGTSLS