Function
Gonad-specific protein essential for germline development to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process in both germline and somatic gonadal tissues by mediating the repression of transposable elements during meiosis. Required for primary piRNA biogenesis in both germline and somatic gonadal tissues.
Sequence
MESESSQDDWSAFDPMSREYYDQVGNRYTNESGQKLIMEAPLPPKDEKEQRATRQAKYPYLVVPKSSPYVTEKMLINFFGRALIKEMEFRRLSRVYFVYFENIASLETAQQRVQRYPNLIKCITGRPQKEREITSDPVTSTEPMPTPGPAISATERTPVNHNREVPISTGGQNHPEFFRPPLVTKDDYKRGSLLATNDPIQRYLNVKYEFALERHDIYKLKDETRIPQVVLHFRSGRTIPLSTVAVTEEDKTKSLLEDGVSKCVVCQNWTDTFCKLCKMPFCNASCFADVAEQHKQACGKGEILNLDEKVGRKYPKPGLPPSGSKVRITAFEQTNVVYVRSADIQIDIAYYTVLTEVMMLGKDASKLQSTPVCGQIVLYKFEGHMSRAMVLNVDNIKEIYVVFIDFGSVEVTQLERLYECSSYLAGLTCYPVAVKLRGVPRRFVGPNIREVMYELDQSLVFNIKYSSREYDTSKGMQVVVMTEIDINRSLNRLFKTILTPVEPSVSDLGYKEDCLPYIPLHCGKNINVVVMDNTFIQCGFIYCTSIDLAYEVTKMQRDIQEYGEKIAKCATYAPPINELCIAKYEGKWRRGLSVELVGDGYPSILFIDYGNIVPTHVTDIRPYPPQFIFPIMTTQLDLIGVPEKPTDEQIKWLDKNYPIGSVITCSEITFDEETNSYSTRIEKLQEFLSLD