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vma-6

Gene
vma-6
Protein
V-type proton ATPase subunit d
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Length
364 amino acids
Function
Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. The active enzyme consists of a catalytic V1 domain attached to an integral membrane V0 proton pore complex. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores (By similarity).
Similarity
Belongs to the V-ATPase V0D/AC39 subunit family.
Mass
41.008 kDa
Sequence
MEGLLFNVNNGYIEGIVRGYRNSLLTSTNYTNMTQCESIDDLKLQLGPAYGDFLASLPPKPSTSALAAKTTDKLVSEFRYVRANAAGSLAKFMDYLTYGYMIDNVALLITGTLHERDTRELLERCHPLGWFETMPVLCVATNIEELYNSVMIETPLAPYFKSSLSLQDLDELNIEIVRNTLYKNYLEDFYHFVNTHPDMAGTPTAEVMSELLEFEADRRAINITLNSFGTELSKADRKKLYPNFGQLYPEGTLMLSRADDFEGVRLAVEGVADYKSFFDAAGLGGGPSGPGNMGGGGTEGKSLEDMFYQKEMEISKMAFTRQFTYAIVYAWVKLREQEIRNITWIAECIAQNQKERINNYISVF