vlp19

Gene

vlp19

Protein

Variable large protein 19

Organism

Borrelia hermsii

Length

349 amino acids

Function

The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.

Similarity

Belongs to the variable large protein (Vlp) family. Gamma subfamily.

Mass

35.222 kDa

Fragment

single

Sequence

MRKRISAIIMTLFMVLVSCNSGGVAEDPQSKFLKSVIDLGNDFLNVFTSFGDIVSKVLGFSTETKKSDVGAYFKTIQDTIQGTKDKLNKIVTDMKREGNPNASATETAVKTLIDNTLDKIIEGAKTVSDAIGDASDPIANVAAQNAAGAAGTEVDKLVKGIKTIVDVVLKGVGSANAGDDKKAEDGNTARTAAAGDGEAGKLFTAGAGAAGDANNAKKVAADAAKAVGAVTGADILQAMIKDNGDAAKLATAQNAGAAPKDGAIAGGIALRVMAKGGKFAGPSAAADDAVTAIKGAAISAITKALDTLTIAIRKTIDAGLKTVKEAMKINANDTPISPEQNTPKATTNN

Protein

Variable large protein 19: vlp19