vlp10

Gene

vlp10

Protein

Variable large protein 10

Organism

Borrelia hermsii

Length

366 amino acids

Function

The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.

Similarity

Belongs to the variable large protein (Vlp) family. Beta subfamily.

Mass

37.667 kDa

Sequence

MRKRISAIIMTLFMVLASCSNQLEAEKLAAESKNTFFDSLVKIGQGFQDIFGILEMQLGDALGFNAVKSGDKKSKVGEHFKKIGDGLTTTKDKLKELSNKISEAKNANSSTIEAVKSAINSASDVFEQLITALTKLADTAKEAGDTNIGDNADAVPGAAEKTGVEAIIAGVKDIIGAAEKSGVKIEYGNAGDPIATAANTTDALAVLGGNTAKATQGAGDKLAFEVSKADPWAIIDKIKNAKAADGIQLDAGEKDAGTLAASNNNASANAGAESNAASSSSWLFLMQLSKGGKFSAAVADAGAVKAAAVSAVNKVLGVLDFIIRKTVSSNLDKIREAVKGIKYSEITETDATESGDAQPITNKSSN

Protein

Variable large protein 10: vlp10