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virB3

Gene
virB3
Protein
Type IV secretion system protein virB3
Organism
Brucella abortus (strain 2308)
Length
116 amino acids
Function
The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice.
Similarity
Belongs to the virB3 family.
Mass
13.082 kDa
Sequence
MTTAPQESNARSAGYRGDPIFKGCTRPAMLFGVPVIPLVIVGGSIVLLSVWISMFILPLIVPIVLVMRQITQTDDQMFRLLGLKAQFRLIHFNRTGRFWRASAYSPIAFTKRKRES

Gene
virB3
Protein
Type IV secretion system protein virB3
Organism
Brucella abortus biovar 1 (strain 9-941)
Length
116 amino acids
Similarity
Belongs to the virB3 family.
Mass
13.082 kDa
Sequence
MTTAPQESNARSAGYRGDPIFKGCTRPAMLFGVPVIPLVIVGGSIVLLSVWISMFILPLIVPIVLVMRQITQTDDQMFRLLGLKAQFRLIHFNRTGRFWRASAYSPIAFTKRKRES

Gene
virB3
Protein
Type IV secretion system protein virB3
Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Length
116 amino acids
Similarity
Belongs to the virB3 family.
Mass
13.082 kDa
Sequence
MTTAPQESNARSAGYRGDPIFKGCTRPAMLFGVPVIPLVIVGGSIVLLSVWISMFILPLIVPIVLVMRQITQTDDQMFRLLGLKAQFRLIHFNRTGRFWRASAYSPIAFTKRKRES

Gene
virB3
Protein
Type IV secretion system protein virB3
Organism
Brucella suis biovar 1 (strain 1330)
Length
116 amino acids
Function
The VirB system could be required for the establishment of the replication niche in the host.
Similarity
Belongs to the virB3 family.
Mass
13.082 kDa
Sequence
MTTAPQESNARSAGYRGDPIFKGCTRPAMLFGVPVIPLVIVGGSIVLLSVWISMFILPLIVPIVLVMRQITQTDDQMFRLLGLKAQFRLIHFNRTGRFWRASAYSPIAFTKRKRES

Gene
virB3
Protein
Protein virB3
Organism
Agrobacterium fabrum (strain C58 / ATCC 33970)
Length
108 amino acids
Function
VirB proteins are suggested to act at the bacterial surface and there play an important role in directing T-DNA transfer to plant cells.
Similarity
Belongs to the virB3 family.
Mass
11.596 kDa
Sequence
MNDRLEEATLYLAATRPALFLGVPLTLAGLLVMFAGFVIVIVQNPLYEVVLVPLWFGARLVVERDYNAASVVLLFLQTAGRSVDGLIWGGASVSPNPIKVPARGRGMA

Gene
virB3
Protein
Protein virB3
Organism
Agrobacterium tumefaciens (strain 15955)
Length
108 amino acids
Function
VirB proteins are suggested to act at the bacterial surface and there play an important role in directing T-DNA transfer to plant cells.
Similarity
Belongs to the virB3 family.
Mass
11.76 kDa
Sequence
MNDRLEEATLYLAATRPALFLGVPLTLAGLFMMFAGFVIVIVQNPLYEVVLAPLWFGARLIVERDYNAASVVLLFLRTAGRSIDSAVWGGATVSPNPIRVPPRGRGMV

Gene
virB3
Protein
Protein virB3
Organism
Rhizobium radiobacter
Length
108 amino acids
Function
VirB proteins are suggested to act at the bacterial surface and there play an important role in directing T-DNA transfer to plant cells.
Similarity
Belongs to the virB3 family.
Mass
11.76 kDa
Sequence
MNDRLEEATLYLAATRPALFLGVPLTLAGLFMMFAGFVIVIVQNPLYEVVLAPLWFGARLIVERDYNAASVVLLFLRTAGRSIDSAVWGGATVSPNPIRVPPRGRGMV

Gene
virB3
Protein
Type IV secretion system protein virB3
Organism
Bartonella henselae (strain ATCC 49882 / DSM 28221 / Houston 1)
Length
103 amino acids
Function
The type IV secretion system VirB/VirD4 is a major virulence determinant for subversion of human endothelial cell (HEC) function. VirB-dependent changes of HEC include massive cytoskeletal rearrangements, a proinflammatory activation by nuclear factor NF-kappa-B, inhibition of early and late events of apoptosis, leading to an increased cell survival, and, at high infection doses, a cytostatic or cytotoxic effect, which interfers with a potent VirB-independent mitogenic activity. These changes of HEC require the T4S coupling protein VirD4 and at least one of the effector proteins BepA-G. VirB3 may play a role in stabilization of pilus structure.
Similarity
Belongs to the virB3 family.
Mass
11.705 kDa
Sequence
MNEDPLFLACTRPAMFAGVTMEAMAFNVMATSILFILTSGFTMIGLGIGLHFVLREITKHDHNQFRVLFAWLNTRGKQKNLNRWGGGSTSPLRLIRTYEELNR

Gene
virB3
Protein
Type IV secretion system protein virB3
Organism
Bartonella quintana (strain Toulouse)
Length
103 amino acids
Function
Component of the type IV secretion system VirB/VirD4 which could be a major virulence determinant for subversion of human endothelial cell (HEC) function. VirB3 may play a role in stabilization of pilus structure.
Similarity
Belongs to the virB3 family.
Mass
11.686 kDa
Sequence
MNEDTLFLACTRPATFAGVTMEGMALNVMATSILFILTSNFTMIGLGIGLHFVLREVTKYDHNQFRVLFAWLNTRGKQKNLTRWGGGSTSPLRLIRTYKELNR