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vex1

Gene
vex1
Protein
Homeobox protein vex1
Organism
Xenopus laevis
Length
285 amino acids
Function
Transcriptional repressor. Acts in a ventral signaling pathway downstream of bmp4 to antagonize the Spemann organizer and ventrally pattern the embryonic mesoderm. Represses transcription of the dorsal genes gsc and otx2.
Mass
32.243 kDa
Sequence
MEKRPYSVEWLSESSQRKAVYSNADLLGYKSGNPDKESNISLPSRATGPTLPSVDYREKENYCVRNVQNEERSPPVKDQLHSQPAPQELDTSRRALMVVPACERSTDQGNKVTGTTDTNKKAKPVCDEDAAARARTKFSPEQLEELERSFKENRYIGSSEKRRLSKVLKLSETQIKTWFQNRRMKFKRQTQDARVDAFFSGLYVPYYGYPDLPTPGYSVQPEFSVLAPHTMAAPSLPFGPLQSTVISPGLHPTAIPSANLGSYPYSSMLVHPMLNEPKRQRYSPY

Gene
vex1
Protein
Homeobox protein vex1
Organism
Xenopus tropicalis
Length
282 amino acids
Function
Transcriptional repressor. Acts in a ventral signaling pathway downstream of bmp4 to antagonize the Spemann organizer and ventrally pattern the embryonic mesoderm. Represses transcription of the dorsal genes gsc and otx2 (By similarity).
Mass
32.069 kDa
Sequence
MEKRPYSVAWLSESSQRKPLCTNVDLLGYKSGNPDLPPNREYNVSLPSRVILPTPDYREKENYCGRNVHNGERSPPVRDQLHFHPAPQELTTSRRTSIEVSAESSTDQRVIGMTDTNKKTISVCDEDAASRARTKFTAEQLEELEKSFKENRYIGSSEKRRLSKVLKLSENQIKTWFQNRRMKFKRQTQDARVEAFFSGLYLPYYGYPDLPTPGYSVQSEFPVLAPQTMAASSIPFGPLHSTVMSPGLHPAIPSANLGSYPCSSMLVRPILNEPTRQRYSPY