Protein
Ribonuclease VapC37
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Function
Probable toxic component of a type II toxin-antitoxin (TA) system. An RNase. Upon expression in M.smegmatis inhibits colony formation. The putative cognate antitoxin is VapB37.
Similarity
Belongs to the PINc/VapC protein family.
Sequence
MKIVDANVLLYAVNTTSEHHKPSLRWLDGALSGADRVGFAWVPLLAFVRLATKVGLFPRPLPREAAITQVADWLAAPSAVLVNPTVRHADILARMLTYVGTGANLVNDAHLAALAVEHRASIVSYDSDFGRFEGVRWDQPPALL