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vapC21

Gene
vapC21
Protein
Ribonuclease VapC21
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
138 amino acids
Function
Toxic component of a type II toxin-antitoxin (TA) system. An RNase. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB21 (By similarity).
Similarity
Belongs to the PINc/VapC protein family.
Mass
15.773 kDa
Sequence
MTTRYLLDKSAAYRAHLPAVRHRLEPLMERGLLARCGITDLEFGVSARSREDHRTLGTYRRDALEYVNTPDTVWVRAWEIQEALTDKGFHRSVKIPDLIIAAVAEHHGIPVMHYDQDFERIAAITRQPVEWVVAPGTA

Gene
vapC21
Protein
Ribonuclease VapC21
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
138 amino acids
Function
Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB21.
Similarity
Belongs to the PINc/VapC protein family.
Mass
15.773 kDa
Sequence
MTTRYLLDKSAAYRAHLPAVRHRLEPLMERGLLARCGITDLEFGVSARSREDHRTLGTYRRDALEYVNTPDTVWVRAWEIQEALTDKGFHRSVKIPDLIIAAVAEHHGIPVMHYDQDFERIAAITRQPVEWVVAPGTA