vapC1

Ribonuclease VapC1

194 amino acids

Toxic component of a type II toxin-antitoxin (TA) system. An RNase.

Belongs to the PINc/VapC protein family.

21.855 kDa

MPWVGSQFHKGDAQTIMALSNVLYQVLIALGMIYVIDTSAIISRNLNLLEGDLMFPSSVIGEIKKGKLRYMIDVLLPMIRVASPDHEYLKIVEETAAKTGDLMNLSQTDKDVLALALQYDATIVTDDYSIQNVASYLNLGFLNANIKRIDKQIAWIYRCTGCKKVFPGPVKVCDICGHEVKRHYDKRKSMIRKV

vapC1

Ribonuclease VapC1

144 amino acids

Toxic component of a type II toxin-antitoxin (TA) system. An RNase.

Belongs to the PINc/VapC protein family.

16.6 kDa

MNSEKVFVDGNVIVDIFDERRVNHKYSVQAIRILLANKFDLLTSSDLITTVYYVLSKIDKKKALSDIKEVVNILEIIPFGKAEVEKAIELMEGDKNFKDLEDTLQYVLAKKEGCKLILSNDKSFYSPDIEVLTTEEFCERWNTL

vapC1

Ribonuclease VapC1

136 amino acids

Toxic component of a type II toxin-antitoxin (TA) system. An RNase. Its cognate antitoxin is VapB1 (By similarity).

Belongs to the PINc/VapC protein family.

16.21 kDa

MKILKKLKKKLEKEESKILVDTSVLIDYFKKRRLEELGGEAISIITAVEFIRGISEHKQEQVLNIFKELFEIVYIDEEIIIPFSKIYRQLKKRGMLIDDADLYIACTAIIKNYPLWTKNKKHFERLKEFGLKIYDK

vapC1

Ribonuclease VapC1

134 amino acids

Toxic component of a type II toxin-antitoxin (TA) system. Upon expression in E.coli inhibits growth in liquid culture. Its toxic effect is neutralized by coexpression with antitoxin VapB1. Degrades RNA but not ss- or ds-DNA in vitro, degradation is inhibited by VapB1 antitoxin.

Belongs to the PINc/VapC protein family.

15.692 kDa

MIYMLDTNIIIYLMKNRPKIIAERVSQLLPNDRLVMSFITYAELIKGAFGSQNYEQSIRAIELLTERVNVLYPNEQICLHYGKWANTLKKQGRPIGNNDLWIACHALSLNAVLITHNVKEFQRITDLQWQDWTK

vapC1

Ribonuclease VapC1

134 amino acids

Toxic component of a type II toxin-antitoxin (TA) system (PubMed:25391136, PubMed:27672196). Acts as an RNase (Probable). Its toxic effect is neutralized by cognate antitoxin VapB1 (PubMed:25391136, PubMed:27672196) but not by non-cognate antitoxin VapB2 (PubMed:25391136, PubMed:27672196).

Belongs to the PINc/VapC protein family.

15.692 kDa

MIYMLDTNIIIYLMKNRPKIIAERVSQLLPNDRLVMSFITYAELIKGAFGSQNYEQSIRAIELLTERVNVLYPNEQICLHYGKWANTLKKQGRPIGNNDLWIACHALSLNAVLITHNVKEFQRITDLQWQDWTK

vapC1

Ribonuclease VapC1

134 amino acids

Toxic component of a type II toxin-antitoxin (TA) system. Acts as an RNase, its toxic effect is neutralized by VapB1 antitoxin (By similarity).

Belongs to the PINc/VapC protein family.

15.726 kDa

MIYMLDTNIIIYLMKNRPKIIAERVSQLLPNDRLVMSFITYAELIKGAFGSQNYEQSIRAIELLTERVNVLYPNEQICLHYGKWANTLKKQGRPIGNNDLWFACHALSLNAVLITHNVKEFQRITDLQWQDWTK

vapC1

Ribonuclease VapC1

134 amino acids

Toxic component of a type II toxin-antitoxin (TA) system. Has ssRNase activity. Upon expression in E.coli inhibits growth in liquid culture; this toxic effect is neutralized by coexpression with cognate antitoxin VapB1. Its RNase activity is partially inhibited in vitro by VapB1 (PubMed:22046301).

Belongs to the PINc/VapC protein family.

15.177 kDa

MGLIIDTSIIIALERGKVSTKQWSHYGQAYISPIVLTELLIGVDRVNNENKRIKCLAFIEYVKSLFTILPFGIEEVYTYARIINDLYKQRITIGTHDMLIAATAITHGYSLLTLNVKDFKRIQGLEVLTVSSKD

vapC1

Ribonuclease VapC1

133 amino acids

Toxic component of a type II toxin-antitoxin (TA) system. The cognate antitoxin is VapB1 (By similarity).

Belongs to the PINc/VapC protein family.

14.372 kDa

MDECVVDAAAVVDALAGKGASAIVLRGLLKESISNAPHLLDAEVGHALRRAVLSDEISEEQARAALDALPYLIDNRYPHSPRLIEYTWQLRHNVTFYDALYVALATALDVPLLTGDSRLAAAPGLPCEIKLVR

vapC1

Ribonuclease VapC1

133 amino acids

Toxic component of a type II toxin-antitoxin (TA) system. The cognate antitoxin is VapB1 (By similarity). Has ribonuclease activity.

Belongs to the PINc/VapC protein family.

14.372 kDa

MDECVVDAAAVVDALAGKGASAIVLRGLLKESISNAPHLLDAEVGHALRRAVLSDEISEEQARAALDALPYLIDNRYPHSPRLIEYTWQLRHNVTFYDALYVALATALDVPLLTGDSRLAAAPGLPCEIKLVR