vapB15

Gene

vapB15

Protein

Antitoxin VapB15

Organism

Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

Length

80 amino acids

Function

Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the toxic effect of cognate toxin VapC15.

Mass

8.884 kDa

Sequence

MYSGVVSRTNIEIDDELVAAAQRMYRLDSKRSAVDLALRRLVGEPLGRDEALALQGSGFDFSNDEIESFSDTDRKLADES

Protein

Antitoxin VapB15: vapB15

Gene

vapB15

Protein

Antitoxin VapB15

Organism

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Length

80 amino acids

Function

Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC15 (PubMed:20011113). Partially inhibits the RNase activity of VapC15 (PubMed:25450593).

Mass

8.884 kDa

Sequence

MYSGVVSRTNIEIDDELVAAAQRMYRLDSKRSAVDLALRRLVGEPLGRDEALALQGSGFDFSNDEIESFSDTDRKLADES

Protein

Antitoxin VapB15: vapB15

Gene

vapB15

Protein

Putative antitoxin VapB15

Organism

Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)

Length

71 amino acids

Function

Possibly the antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is VapC15 (Potential).

Similarity

Belongs to the UPF0330 family.

Mass

8.438 kDa

Sequence

MPTKTITITLEAYERLKREKREGESFSDVIIRLTEKRRDLLEFAGKWKDSGEEIEKIILEGRKEFDKHVLS

Protein

Putative antitoxin VapB15: vapB15