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vapB1

Gene
vapB1
Protein
Antitoxin VapB1
Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)
Length
103 amino acids
Function
Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in E.coli neutralizes the effect of cognate toxin VapC1, partially inhibits the RNase activity of VapC1 in vitro.
Mass
12.156 kDa
Sequence
MQLFLRINMAQIIRATEFVRSFSDIMNRVYYKGESFDVQKGNHIVARITPAETKPSIAVRDLEEAFKNGPHLDPEDADQFMKDIEEIRRSTRQDIKKLVERWD
Protein
Antitoxin VapB1: vapB1

Gene
vapB1
Protein
Putative antitoxin VapB1
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
79 amino acids
Function
Antitoxin component of a possible type II toxin-antitoxin (TA) system. The cognate toxin is VapC1.
Mass
8.718 kDa
Sequence
MATIQVRDLPEDVAETYRRRATAAGQSLQTYMRTKLIEGVRGRDKAEAIEILEQALASTASPGISRETIEASRRELRGG
Protein
Putative antitoxin VapB1: vapB1

Gene
vapB1
Protein
Antitoxin VapB1
Organism
Haemophilus influenzae (strain R2866)
Length
78 amino acids
Function
Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in E.coli neutralizes the effect of toxin VapC1. In vitro inhibits the RNase activity of VapC1.
Similarity
Belongs to the VapB family.
Mass
9.037 kDa
Sequence
MLTKVFQSGNSQAVRIPMDFRFDVDTVEIFRKENGDVVLRPVSKKTDDFLALFEGFDETFIQALEARDDLPPQERENL
Protein
Antitoxin VapB1: vapB1

Gene
vapB1
Protein
Antitoxin VapB1
Organism
Haemophilus influenzae (strain 86-028NP)
Length
78 amino acids
Function
Antitoxin component of a type II toxin-antitoxin (TA) system (PubMed:25391136, PubMed:27672196). Neutralizes the effect of cognate toxin VapC1 (PubMed:25391136, PubMed:27672196) but not non-cognate toxin VapC2 (PubMed:27672196).
Similarity
Belongs to the VapB family.
Mass
9.037 kDa
Sequence
MLTKVFQSGNSQAVRIPMDFRFDVDTVEIFRKENGDVVLRPVSKKTDDFLALFEGFDETFIQALEARDDLPPQERENL
Protein
Antitoxin VapB1: vapB1

Gene
vapB1
Protein
Antitoxin VapB1
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Length
78 amino acids
Function
Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of toxin VapC1 (By similarity).
Similarity
Belongs to the VapB family.
Mass
9.037 kDa
Sequence
MLTKVFQSGNSQAVRIPMDFRFDVDTVEIFRKENGDVVLRPVSKKTDDFLALFEGFDETFIQALEARDDLPPQERENL
Protein
Antitoxin VapB1: vapB1

Gene
vapB1
Protein
Putative antitoxin VapB1
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Length
64 amino acids
Function
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is VapC1 (Potential).
Mass
7.775 kDa
Sequence
MISAKSKTKRITITFEIPEDIDAKKFKDDVKRYVRYKLLANKLYELLEGENIEEIEEEIRKRRE